Volume 12 Supplement 1

Abstracts from the 2012 PLA Emergency Medicine Annual Congress

Open Access

Clinical usefulness of T-SPOT.TB in the diagnosis tuberculosis in emergency patients

BMC Emergency Medicine201212(Suppl 1):A7

DOI: 10.1186/1471-227X-12-S1-A7

Published: 18 December 2012

Objective

To evaluate the diagnostic value of an interferon-gamma release assay T-SPOT.TB in tuberculosis of emergency patients.

Methods

The emergency patients with suspected tuberculosis received T-SPOT.TB assay in the peripheral blood mononuclear cells(PBMCs).

Results

T-SPOT.TB assay, PPD, anti-TB antibody test, M tuberculosis polymerase chain reaction, acid-fast bacilli stain and cultures for M tuberculosis were positive in 96.8%(31/32), 43.7%(14/32), 21.8%(7/32), 15.6%(5/32), 13.0%(3/23) and 4.3%(1/23), respectively, of patients with active tuberculosis. The sensitivity and specificity of the T-SPOT.TB were 96.8% and 98.3%.

Conclusions

T-SPOT.TB assay is a rapid and high-sensitive tests for diagnosing tuberculosis in emergency patients.

Authors’ Affiliations

(1)
Department of Emergency Xijing Hospital, the Fourth Military Medical University

Copyright

© Xiao-min et al; licensee BioMed Central Ltd. 2012

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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