Table 1 Baseline characteristics
Characteristics | TXA (n =120) | Placebo (n = 118) |
|---|---|---|
Age at randomization (years) | 34.8 (16.0) | 34.1 (15.3) |
Male | 103 (86%) | 107 (91%) |
Glasgow coma scale (GCS) severity: Moderate (9 – 12) Severe (4 – 8) | 52 (53%) | 47 (47%) |
68 (49%) | 71 (51%) | |
Baseline haematocrit (volume %) | 38 (7.4) | 38 (6.7) |
Time since injury (hours) | 6.6 (1.69) | 7.1 1.29) |
Isolated TBI injury | 20 (17%) | 16 (14%) |
Polytrauma with TBI injury | 100 (83%) | 102 (86%) |
Mean injury severity score (range) | 23.3 (9–43) | 24.8 (9–43) |
Midline shift (>3 mm) on first CT (mm) | 2 (0.02%) | 3 (0.03%) |
Basal cistern compression on first CT | 54 (45%) | 53 (45%) |