Table 2 Sensitivity, specificity, positive and negative predictive values for the diagnosis of ACS with clinical myocardial infarction at presentation
From: Which diagnostic tests are most useful in a chest pain unit protocol?
Sensitivity (95% CI) | Specificity (95% CI) | Positive predictive value (95% CI) | Negative predictive value (95% CI) | |
|---|---|---|---|---|
Serial ECG & ST monitoring N = 690 | 33.3% (19.2 to 51.2) | 95.3% (93.4 to 96.7) | 24.4% (13.8 to 39.3) | 96.9% (95.3 to 98.0) |
Initial CK-MB(mass) N = 687 | 63.3% (45.5 to 78.1) | 97.0% (95.3 to 98.0) | 48.7% (33.9 to 63.8) | 98.3% (97.0 to 99.0) |
Delayed CK-MB(mass) N = 601 | 95.7% (79.0 to 99.2) | 96.2% (94.3 to 97.5) | 50.0% (35.8 to 64.2) | 99.8% (99.0 to 100) |
Delta CK-MB(mass) N = 601 | 95.7% (79.0 to 99.2) | 98.4% (97.0 to 99.1) | 70.0% (53.4 to 83.9) | 99.8% (99.0 to 100) |
Any positive CK-MB(mass) N = 601 | 100% (88.6 to 100) | 95.6% (93.7 to 96.9) | 50.8% (38.3 to 63.2) | 100% (99.4 to 100) |
Troponin T > = 0.1 ng/ml N = 686 | 83.3% (66.4 to 92.7) | 98.8% (97.7 to 99.4) | 75.8% (59.0 to 87.2) | 99.3% (98.3 to 99.7) |
Troponin T > = 0.03 ng/ml N = 686 | 96.4% (82.3 to 99.4) | 95.9% (94.1 to 97.2) | 50.0% (37.1 to 62.9) | 99.8% (99.1 to 100) |