Table 2 Summary of the relevant age limits

Sepsis, Temperature & Immune System

Greater body surface & thinner skin, heat generation by brown adipose tissue [13]

Newborn

Special diagnostic scheme for elevated temperature [13]

Newborn

Postoperative muscle tremor for heat generation [13]

Starting from 6 years

Monocytes restricted to few cytokines [14]

Newborn

Immune system more in an anti-inflammatory mode [14]

Up to 3 years

Differentiation of B lymphocytes [15]

Up to 5 years

Differentiation of the innate immune system [14]

Starting from 5 years of age - approx. 13 years of age

Respiration

Greatest formation of new alveoli [16]

Up to the age of 2

Completion of alveolar formation[16]

Starting from 12 years

Traumatic brain injury

Unclear oncogenic effect unsuitable for initial assessment [17]

Up to 2 years

Glasgow coma scale unsuitable for initial assessment [18]

Up to 3 years

Immature cranial calvaria, higher water content, heavy head & weak musculature [19]

Up to 5 years

Often different accident mechanism - often involved as pedestrian in the accident [20]

Up to 6 years

“Kennard-Principle” Better outcome with traumatic brain injury [21]

Up to 12 years