Assessment of renal function indexes in methamphetamine or tramadol intoxication adults to the emergency departments: a systematic review and meta-analysis

Table 3 Pooled weighted mean, heterogeneity and publication bias according to renal dysfunction test using Knapp-Hartung adjustment for random effect model

Renal clinical index	Intoxication agent	Number of studies	Weighted Mean, (95%, CI)	Heterogeneity test		Publication bias
Renal clinical index	Intoxication agent	Number of studies	Weighted Mean, (95%, CI)	I²%	Chi-square	Egger’s	Begg’s
BUN	Tramadol	4	29.85 (21.25–38.46)	0.0	0.705	0.949	0.99
BUN	MET	4	31.64 (12.71–50.57)	90.03	0.001	0.073	0.308
Creatinine	Tramadol	4	1.04 (0.84–1.25)	0.0	0.821	0.546	0.734
Creatinine	MET	4	1.35 (1.13–1.56)	0.0	0.530	0.185	0.99
CPK	Tramadol	2	397.68 (376.42-418.94)	0.0	0.981	0.991	-
CPK	MET	4	909.87 (549.98-1269.76)	0.0	0.910	0.585	0.174

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