| PPi < 40mmHg (n = 292) | PPi ≥ 40mmHg (n = 238) | p value |
---|---|---|---|
Demographics | |||
Age (years) | 69 ± 14 | 70 ± 15 | 0.750 |
Male gender | 190 (65%) | 151 (63%) | 0.699 |
BMI (kg.m− 2) | 29.7 ± 5.2 | 25.4 ± 6.4 | 0.239 |
Hypertension | 125 (43%) | 133 (56%) | 0.763 |
Chronic cardiac failure | 75 (26%) | 179 (75%) | 0.814 |
Coronary heart failure | 64 (22%) | 198 (83%) | 0.141 |
Diabetes Mellitus | 77 (26%) | 164 (69%) | 0.232 |
Cancer history | 116 (40%) | 168 (71%) | 0.013 |
COPD | 45 (15%) | 204 (86%) | 0.718 |
Chronic Renal Failure | 38 (13%) | 201 (84%) | 0.406 |
Immunosuppression | 110 (38%) | 159 (67%) | 0.285 |
Prehospital | |||
Initial SBP (mmHg) | 98 ± 18 | 117 ± 28 | < 10− 3 |
Initial DBP (mmHg) | 52 ± 17 | 64 ± 20 | < 10− 3 |
Initial MAP (mmHg) | 62 ± 17 | 82 ± 23 | < 10− 3 |
Initial HR (beats.min− 1) | 113 ± 28 | 116 ± 29 | 0.371 |
Initial RR (movements.min− 1) | 28 [20–35] | 31 [24–38] | 0.012 |
Initial pulse oximetry (%) | 92 [85–96] | 92 [85–96] | 0.152 |
Initial body core temperature (°C) | 38.3 [36.4–39.0] | 38.4 [36.9–39.2] | 0.134 |
Initial Glasgow coma scale | 15 [13–15] | 15 [12–15] | 0.127 |
Initial blood lactate (mmol.l− 1) | 6.2 ± 3.6 | 5.6 ± 3.2 | 0.103 |
Fluid expansion (ml) | 1000 [500–1200] | 750 [500–1000] | 0.154 |
Norepinephrine administration | 106 (36%) | 189 (79%) | < 10− 3 |
Prehospital AB administration | 84 (29%) | 190 (80%) | 0.023 |
Prehospital duration (min) | 67 ± 34 | 74 ± 34 | 0.017 |
Final SBP (mmHg) | 102 ± 23 | 111 ± 26 | < 10− 3 |
Final DBP (mmHg) | 61 ± 18 | 64 ± 18 | 0.111 |
Final MAP (mmHg) | 75 ± 19 | 79 ± 20 | 0.019 |
Final HR (beats.min− 1) | 107 ± 24 | 108 ± 26 | 0.379 |
Final RR (movements.min− 1) | 24 [19–30] | 25 [20–32] | 0.089 |
Final pulse oximetry (%) | 97 [95–99] | 97 [94–99] | 0.219 |
Final body core temperature (°C) | 38.2 [36.1–39.4] | 38.1 [36.3–39.1] | 0.932 |
Final Glasgow coma scale | 15 [14–15] | 15 [13–15] | 0.204 |
Final blood lactate (mmol.l− 1) | 4.2 ± 3.2 | 4.3 ± 3.5 | 0.576 |
Hospital | |||
SOFA score | 6 [4–9] | 5 [2–8] | 0.104 |
In-ICU length of stay (days) | 4 [2–8] | 4 [1–8] | 0.940 |
In-hospital length of stay (days) | 10 [5–17] | 10 [5–18] | 0.923 |