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Table 3 Demographics on hospital arrival and in-hospital treatments of patients before and after the COVID-19 pandemic

From: Impact of the COVID-19 pandemic on prehospital and in-hospital treatment and outcomes of patients after out-of-hospital cardiac arrest: a Japanese multicenter cohort study

Variable

Pre-pandemic

(n = 2015)

Post-pandemic

(n = 5023)

p-value

ECG on hospital arrival

    

< 0.01

 VF

89/2015

(4.4)

163/5023

(3.2)

 

 Pulseless VT

7/2015

(0.3)

17/5023

(0.3)

 

 PEA

388/2015

(19.3)

912/5023

(18.2)

 

 Asystole

1290/2015

(64.0)

3461/5023

(68.9)

 

 ROSC

241/2015

(12.0)

463/5023

(9.2)

 

BT on hospital arrival, ºC

35.6

(34.6–36.3)

35.8

(34.8–36.4)

0.05

GCS on hospital arrival

    

0.31

 3

1951/2015

(96.8)

4886/5023

(97.3)

 

 4–15

64/2015

(3.2)

137/5023

(2.7)

 

Blood tests

     

 Lactate (mmol) †

1.8

(1.3–143.0)

1.9

(1.3–150.0)

0.11

 WBC (103/µL)

9.8

(7.3–12.7)

9.4

(7.0-12.5)

< 0.01

 Hb (g/dL)

12.0

(10.0-13.7)

11.9

(10.0-13.8)

0.35

 pH

6.85

(6.72–6.99)

6.85

(6.72–6.98)

0.66

 PaCO2 (mmHg)

86.4

(66.4–113.0)

87.8

(66.3–114.0)

0.19

 PaO2 (mmHg)

33.1

(18.0-68.3)

33.0

(18.2–64.0)

0.48

 HCO3 (mEq/L)

15.1

(11.1–18.9)

15.3

(11.6–18.9)

0.05

 BE (mEq/L)

-19.0

(-24.0 to -13.3)

-19.1

(-24.4 to -13.8)

0.05

Mechanical chest compression

311/2015

(15.4)

833/5023

(16.6)

0.34

Defibrillation

207/2008

(10.3)

484/4997

(9.7)

0.43

ECMO

84/2015

(4.2)

173/5023

(3.4)

0.14

Coronary angiography

146/2015

(7.2)

252/5023

(5.0)

< 0.01

Coronary intervention

62/140

(44.3)

141/250

(56.4)

0.02

IABP

52/2015

(2.6)

95/5023

(1.9)

0.07

Temperature control

127/1943

(6.5)

282/4985

(5.7)

0.16

Medications

     

 Epinephrine

1503/2015

(74.6)

3581/5023

(71.3)

< 0.01

 Amiodarone

121/2015

(6.0)

238/5023

(4.7)

0.03

 Atropine

23/2015

(1.1)

25/5023

(0.5)

< 0.01

 Magnesium sulfate

19/2015

(0.9)

25/5023

(0.5)

0.03

 Nifekalant

9/2015

(0.4)

22/5023

(0.4)

0.96

 Lidocaine

9/2015

(0.4)

17/5023

(0.3)

0.50

 Vasopressin

6/2015

(0.3)

1/5023

(0.0)

< 0.01

  1. Data are shown as the number of positive observations/total number of observations (%) or as median (interquartile range). For each variable, the number of missing observations can be obtained as the difference between the total number of patients in each group and the total number of observations
  2. ECG, electrocardiogram; VF, ventricular fibrillation; VT, ventricular tachycardia; PEA, pulseless electrical activity; ROSC, return of spontaneous circulation; BT, body temperature; GCS, Glasgow coma scale; WBC, white blood cells; Hb, hemoglobin; pH, potential hydrogen; pCO2, carbon dioxide partial pressure; pO2, oxygen partial pressure; HCO3, bicarbonate ion; BE, base excess; ECMO, extracorporeal membrane oxygenation; IABP, intra-aortic balloon pumping
  3. †Lactate was measured in 1349 patients in the pre-pandemic group and 3371 patients in the post-pandemic group