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Table 1 Aggregate mortality results from 13 randomised trials of steroids in head injury published before 1997

From: The CRASH trial protocol (Corticosteroid randomisation after significant head injury) [74459797]

  Steroid Control
No. of patients 1,061 1,087
No. who died 396 422
  (37%) (39%)
  1. Absolute benefit of steroids 2%, indicating 1 death prevented for every 50 patients treated: but these previous trial results are also statistically compatible with there being no real benefit at all (or even a small hazard).