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Table 1 Estimated number of premature trauma deaths averted by TXA per year

From: Avoidable mortality from giving tranexamic acid to bleeding trauma patients: an estimation based on WHO mortality data, a systematic literature review and data from the CRASH-2 trial

 

In-hospital trauma deaths from bleeding

Deaths averted TXA ≤ 1 hour

Deaths averted TXA ≤ 3 hours

   Worldwide

400,467

128,149

112,131

Countries with > 1000 deaths averted

   India

58,801

18,816

16,464

   China

54,241

17,357

15,187

   Brazil

19,187

6,140

5,372

   Russian Federation

16,731

5,354

4,685

   Myanmar

13,193

4,222

3,694

   Iraq

12,786

4,091

3,580

   USA

12,489

3,996

3,497

   Indonesia

11,033

3,531

3,089

   DR Congo

9,373

2,999

2,624

   Sri Lanka

8,979

2,873

2,514

   Pakistan

8,770

2,806

2,456

   Ethiopia

8,768

2,806

2,455

   Nigeria

8,258

2,643

2,312

   Colombia

7,348

2,352

2,058

   Sudan

7,292

2,334

2,042

   Bangladesh

7,210

2,307

2,019

   Mexico

7,059

2,259

1,976

   Philippines

6,119

1,958

1,713

   Thailand

5,572

1,783

1,560

   Afghanistan

4,774

1,528

1,337

   Uganda

4,620

1,478

1,294

   South Africa

4,245

1,359

1,189

   Venezuela

4,172

1,335

1,168

   Kenya

4,029

1,289

1,128

   Tanzania

3,969

1,270

1,111

   Iran

3,921

1,255

1,098