Table 4 Sensitivity, specificity, positive and negative predictive values for the diagnosis of ACS with myocyte necrosis or clinical myocardial infarction at presentation
From: Which diagnostic tests are most useful in a chest pain unit protocol?
Sensitivity (95% CI) | Specificity (95% CI) | Positive predictive value (95% CI) | Negative predictive value (95% CI) | |
|---|---|---|---|---|
Serial ECG & ST monitoring N = 690 | 23.3% (14.4 to 35.4) | 95.7% (93.8 to 97.0) | 34.1% (21.6 to 49.5) | 92.9% (90.7 to 94.6) |
Initial CK-MB(mass) N = 687 | 43.3% (31.6 to 55.9) | 97.9% (96.5 to 98.8) | 66.7% (51.0 to 79.4) | 94.8% (92.8 to 96.2) |
Delayed CK-MB(mass) N = 601 | 63.5% (49.9 to 75.2) | 98.0% (96.4 to 98.9) | 75.0% (60.6 to 85.4) | 96.6% (94.7 to 97.8) |
Delta CK-MB(mass) N = 601 | 55.8% (42.3 to 68.4) | 99.6% (98.7 to 99.9) | 93.5% (79.3 to 98.2) | 96.0% (94.0 to 97.3) |
Any positive CK-MB(mass) N = 601 | 71.7% (59.2 to 81.5) | 97.4% (95.9 to 98.4) | 72.9% (60.4 to 82.6) | 97.3% (95.7 to 98.3) |
Troponin T > = 0.1 ng/ml N = 686 | 55.0% (42.5 to 66.9) | 100% (99.4 to 100) | 100% (89.6 to 100) | 96.0% (94.2 to 97.2) |
Troponin T > = 0.03 ng/ml N = 686 | 89.7% (79.2 to 95.2) | 99.7% (98.8 to 99.9) | 96.3% (87.5 to 99.0) | 99.6% (97.9 to 99.9) |