Anion gap, anion gap corrected for albumin, base deficit and unmeasured anions in critically ill patients: implications on the assessment of metabolic acidosis and the diagnosis of hyperlactatemia

Table 6 Subset of patients with creatinine > 2.0 mg/dl excluded

ROC Area Under the Curve for AG, ACAG & BD Hyperlactatemia defined as serum lactate > 2.5 mmol/L
Variable	ROC AUC	CIs
Anion Gap	0.68	0.59 – 0.77
ACAG	0.71	0.59 – 0.84
Base Deficit	0.77	0.69 – 0.85
ROC Area Under the Curve for AG, ACAG & BD Hyperlactatemia defined as serum lactate > 4.0 mmol/L
Variable	ROC AUC	CIs
Anion Gap	0.90	0.83 – 0.97
ACAG	0.96	0.91–0.99
Base Deficit	0.75	0.62 – 0.88

ISSN: 1471-227X