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Table 2 Area under the curve (diagnostic index) for osmole gap to identify toxic alcohol exposure.

From: An evaluation of the osmole gap as a screening test for toxic alcohol poisoning

Exposure Threshold

AUC (95% CI)

p value

AUC2 - AUC1 (95% CI)

p value

ANTIDOTAL THERAPY

    

   Equation 1

0.736 (0.599, 0.873)

< 0.001

0.049 (-0.001, 0.099)

0.057

   Equation 2

0.785 (0.665, 0.905)

< 0.001

  

HEMODIALYSIS

    

   Equation 1

0.827 (0.715, 0.939)

< 0.001

0.043 (-0.001, 0.086)

0.056

   Equation 2

0.870 (0.784, 0.956)

< 0.001

  
  1. AUC = area under the curve; SE = standard error; CI = confidence interval