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Table 6 Recurrence or delayed onset of severe venom effects

From: Crotaline Fab antivenom appears to be effective in cases of severe North American pit viper envenomation: An integrative review

Publication

Patient Identifying Information

Vials of FabAV for Initial Control

Maintenance Therapy Administered?

Recurrent Severe Venom Effects

Delayed Onset Severe Venom Effects

Cohort Studies

Prospective Data Collection

Bush 2002[10]

Patient 14

6

Yes

Limb swelling

Limb pain

None

Dart 1997[4]

Patient 10

8

No

Fibrinogen < 50 mg/dl

None

Retrospective Data Collection

Ruha 2002[13]

Patient 1

18

No

Protime > 50 sec

None

    

Fibrinogen < 50 mg/dl

 

Mixed Prospective/Retrospective Data Collection

No cases

Non-Cohort Studies

Camilleri 2005[27]

40-year-old Male

N/A

No

None

Platelet count < 50,000/mm3

INR >5

     

Fibrinogen < 50 mg/dl

Fazelat 2008[28]

24-year-old Male

10

Yes

Platelet count < 50,000/mm3

None

Lintner 2006[31]

2-year-old Male

12

No

Platelet count < 50,000/mm3

None

Miller 2002[32]

Case 1

NR

No

None

Fibrinogen < 50 mg/dl

Odeleye 2004[34]

Case 2

N/A

No

INR > 5.0

None

Offerman 2003[35]

42-year-old Male

16

NR

Platelet count < 50,000/mm3

None

Richardson 2007[36]

Case 1

N/A

No

None

Fibrinogen < 50 mg/dl

Seifert 1997[37]

53-year-old Female

6

No

Platelet count < 50,000/mm3

None

Wasserberger 2006[38]

46-year-old Male

N/A

No

Platelet count < 50,000/mm3

None

  1. NR = Not reported
  2. N/A = Not applicable (initial control not obtained)