Table 2 Analgesic efficacy
Time to onset Minutes (95 % CI) | Non-responders Patients (%) | Maximal pain reduction mm on a 100 mm VAS (95 % CI) | Time to max pain reduction Minutes (95 % CI) | |
|---|---|---|---|---|
IN Ketamine (n = 24) | 14.3 (9.8–18.8) | 1 (4 %) | 56 mm VAS | 40.4 min (33.9–46.9) |
IV MO (n = 24) | 8.9 (6.6–11.2) | 1 (4 %) | 59 mm VAS | 33.4 min (26.2–40.6) |
IM MO (n = 27) | 26.0 (20.3–31.7) | 3 (11 %) | 48 mm VAS | 46.7 min (41.1–52.3) |
Aggregate | 16.7 (13.7–19.7) | 5 (6.8 %) | 54 mm VAS | 40.6 min (36.8–44.4) |
P value IN Ketamine vs. IV MO | 0.300 | 0.611 (DF = 2) | 0.300 (DF = 2) | 0.386 |
P value IN Ketamine vs. IM MO | 0.003 | 0.441 | ||
P value IV MO vs. IM MO | 0.000 | 0.019 |