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Table 4 Summary of Secondary Outcomes for the intervention of hypertonic saline

From: The effectiveness of prehospital hypertonic saline for hypotensive trauma patients: a systematic review and meta-analysis

  1. Legend:
  2. Statistically significant finding supporting intervention, Non-statistically significant finding, Statistically significant finding supporting control, Not assessed
  3. Note: MODS Multiple Organ Dysfunction Score
  4. * Defined as survival time beyond survival to hospital discharge
  5. † Pre-specified secondary outcome for intention-to-treat analysis
  6. ‡ Patients were stratified by the post-randomization variable of blood transfusion in the first 24 h post injury. Those patients that received hypertonic saline had a 7.4% increase in 28 day mortality compared to those that received normal saline (95% CI 2.5%, 12.2%)
  7. § The mean change (standard deviation) in systolic blood pressure was higher in patients in the hypertonic saline group than in patients in the lactated ringers group (34 ± 46 vs 11 ± 49 mmHg, p < 0.03)