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Table 2 Laboratory parameters upon ICU admission and IL-6 rate of change after 24 h ICU admission (n = 123)

From: Reduction in the IL-6 level at 24 h after admission to the intensive care unit is a survival predictor for Vietnamese patients with sepsis and septic shock: a prospective study

Laboratory parameters

Survival (n = 48)

Mean ± SD

Non- survival (n = 75)

Mean ± SD

p (Student’s t-test)

Hemoglobin (g/dL)

11.3 ± 2.3

11.0 ± 2.6

0.50

White blood cells (K/mm3)

20.6 ± 14.2

18.1 ± 13.2

0.34

Platelets (K/mm3)

164 ± 126

193 ± 134

0.24

Blood glucose (mg/dL)

129.3 ± 80.8

138.6 ± 77.8

0.55

Blood–urea–nitrogen (mg/dL)

35.7 ± 21.6

45.9 ± 25.1

0.02

Creatinine (mg/dL)

1.97 ± 1.5

2.47 ± 1.6

0.08

Bilirubin (mg/dL)

2.40 ± 2.4

3.34 ± 4.6

0.17

Prothrombin time (s)

16.9 ± 5.4

18.6 ± 10.0

0.27

aPTT (s)

35.9 ± 9.4

42.9 ± 20.8

0.02

pH

7.33 ± 0.1

7.28 ± 0.10

0.04

PaCO2 (mmHg)

35.6 ± 7.8

33.5 ± 9.3

0.21

PaO2 (mmHg)

120.4 ± 79.3

129.9 ± 99.6

0.58

HCO3 (mmol/L)

19.0 ± 4.4

16.4 ± 5.8

0.01

C-reactive protein (mg/L)

123.3 ± 45.7

122.4 ± 60.8

0.93

Procalcitonin (ng/dL)

42.5 ± 109.8

54.4 ± 91.4

0.16

Lactate (mmol/L)

4.2 ± 2.6

5.3 ± 4.3

0.59

IL-6 rate of change

0.8 ± 4.5

−0.7 ± 0.3

0.04

  1. aPTT, activated partial thromboplastin time; PaCO2, arterial pressure of carbon dioxide; PaO2, arterial pressure of oxygen; HCO3, bicarbonate
  2. IL-6 rate of change = (IL-6 (T0) – IL-6 T24)/ IL-6 T0