Benzodiazepines n (%) | Z-drugs n (%) | Methadone n (%) | Buprenorphine n (%) | Opioids class Aa n (%) | Opioids class Bb n (%) | Methylphenidate n (%) | Pregabalin n (%) | Quetiapine n (%) | Others n (%) | All casesc n (%) | |
---|---|---|---|---|---|---|---|---|---|---|---|
Bradypnoea | |||||||||||
(RR < 10)d | 79 (11.4) | 2 (7.7) | 5 (8.3) | 3 (5.7) | 5 (14.3) | – | – | – | – | – | 84 (10.3) |
Tachycardia | |||||||||||
(HR > 99)d | 155 (22.3) | 4 (15.4) | 10 (16.7) | 11 (20.8) | 10 (28.6) | 6 (27.3) | 6 (54.5) | 1 (16.7) | 2 (33.3) | 3 (50.0) | 185 (22.6) |
Bradycardia | |||||||||||
(HR < 50)d | 13 (1.9) | – | – | 1 (1.9) | – | – | – | – | – | – | 13 (1.6) |
Hypertension | |||||||||||
(SBP ≥ 180) | 3 (0.4) | – | 1 (1.7) | – | – | – | – | – | – | – | 3 (0.4) |
Hypotension | |||||||||||
(SBP ≤ 90) | 29 (4.2) | – | 3 (5.0) | 4 (7.5) | 3 (8.6) | – | – | – | 1 (16.7) | – | 36 (4.4) |
Hyperthermia | |||||||||||
(tp ≥ 39.0) | 4 (0.6) | – | 1 (1.7) | – | – | – | – | – | – | 1 (16.7) | 5 (0.6) |
GCS scored,e | |||||||||||
15 | 231 (33.2) | 16 (61.5) | 13 (21.7) | 14 (26.4) | 13 (37.1) | 17 (77.3) | 6 (66.7) | 3 (50.0) | 6 (100) | 5 (83.3) | 283 (34.6) |
8–14 | 444 (63.8) | 10 (38.5) | 43 (71.7) | 39 (73.6) | 21 (60.0) | 4 (18.2) | 3 (33.3) | 2 (33.3) | – | 1 (16.7) | 509 (62.1) |
3–7 | 20 (2.9) | – | 4 (6.7) | – | 1 (2.9) | 1 (4.5) | – | 1 (16.7) | – | – | 24 (2.9) |
Vomiting | 12 (1.7) | 1 (3.8) | 5 (8.3) | 3 (5.7) | 1 (2.9) | 2 (9.1) | 1 (9.1) | – | – | 1 (16.7) | 22 (2.7) |
Headache | 15 (2.2) | 2 (7.7) | 1 (1.7) | 2 (3.8) | 1 (2.9) | 1 (4.5) | – | 1 (16.7) | – | 1 (16.7) | 19 (2.3) |
Anxiety | 17 (2.4) | 1 (3.8) | 1 (1.7) | 3 (5.7) | 1 (2.9) | 2 (9.1) | 2 (18.2) | – | 1 (16.7) | 2 (33.3) | 26 (3.2) |
Hallucinations | 8 (1.1) | 2 (7.7) | 2 (3.3) | 3 (5.7) | 2 (5.7) | – | 2 (18.2) | – | – | – | 16 (2.0) |
Agitation | 77 (11.1) | 1 (3.8) | 10 (16.7) | 9 (17.0) | 6 (17.1) | – | 5 (45.5) | – | – | 1 (16.7) | 95 (11.6) |
Psychosis | 12 (1.7) | 2 (7.7) | 2 (3.3) | 1 (1.9) | 3 (8.6) | 1 (4.5) | 4 (36.4) | – | – | – | 21 (2.6) |
Seizures | 4 (0.6) | – | – | – | – | – | – | – | – | – | 4 (0.5) |
Palpitations | 1 (0.1) | – | – | – | – | 1 (4.5) | 1 (9.1) | – | 3 (50.0) | 2 (33.3) | 7 (0.9) |
Chest pain | 11 (1.6) | – | – | – | 2 (5.7) | 1 (4.5) | – | – | 1 (16.7) | – | 14 (1.7) |
Arrhythmias | 2 (0.3) | 1 (3.8) | – | – | – | – | – | – | – | – | 3 (0.4) |
Total | 696 (100) | 26 (100) | 60 (100) | 53 (100) | 35 (100) | 22 (100) | 11 (100) | 6 (100) | 6 (100) | 6 (100) | 819 (100) |