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Table 1 Demographic, clinical, and laboratory data of the study cohort

From: Serum Copeptin levels in the emergency department predict major clinical outcomes in adult trauma patients

Patient characteristics

All (n = 125)

ISS < =15 (n = 64)

ISS > 15 (n = 61)

P

Age (years)

47 (32–63)

43 (31–60)

56 (35–68)

0.0945

Male sex (n [%])

83 (66.4%)

42 (65.6%)

41 (67.2%)

0.8515

ISS

14 (5–24)

5 (1–9)

25 (21–29)

< 0.0001

GCS

15 (15–15)

15 (15–15)

15 (14–15)

0.0327

Respiratory rate (bpm)

19 (17–22)

18 (16–20)

20 (18–23)

0.0027

Oxygen saturation (%)

98 (95–99)

98 (96–99)

97 (94–99)

0.0249

SBP (mmHg)

129 (113–140)

130 (120–145)

120 (105–139)

0.0001

Heart rate (bpm)

86 (78–98)

80 (76–90)

90 (80–100)

0.0010

WBC (*109/L)

11.5 (9.4–15.7)

10.4 (8.3–12.8)

13.6 (11.1–19.9)

<0.0001

Prothrombin time (ratio)

1.08 (1.04–1.13)

1.06 (1.01–1.09)

1.1 (1.06–1.17)

0.0001

Glucose (mmol/L)

7.0 (5.9–8.6)

6.2 (5.5–7.0)

8.3 (6.9–10.1)

<0.0001

Lactate (mmol/L)

2.05 (1.41–2.89)

1.65 (1.20–2.63)

2.54 (1.69–3.37)

0.0010

Copeptin (pmol/L)

132.0 (39.05–372.38)

58.1 (16.69–142.45)

317.80 (145.58–516.08)

<0.0001

Transfusion (n [%])

18 (14.6%)

1 (1.6%)

17 (28.8%)

<0.0001

Surgery (n [%])

14 (11.4%)

2 (3.1%)

12 (20.3%)

0.0035

Hospitalization (n [%])

108 (87.8%)

50 (78.1%)

58 (98.3%)

0.0006

Hospital length of stay (days)

9 (2–21)

2 (1–8)

18 (11–30)

<0.0001

ICU admission (n [%])

29 (23.6%)

0 (0%)

29 (49.2%)

<0.0001

ICU length of stay (days)

5 (3–11)

0

5 (3–11)

ND

Mortality (n [%])

4 (3.3%)

0 (0%)

4 (6.8%)

0.0536

RTS

7.84 (7.84–7.84)

7.84 (7.84–7.84)

7.84 (7.44–7.84)

0.0001

RTS < 7.84

20 (16.0%)

2 (3.1%)

18 (29.5%)

0.0001

Mechanism of injury

   

0.7177

Road accident

 Car

61 (48.8%)

32 (50.0%)

29 (47.5%)

 

 Motorbike

20 (16.0%)

10 (15.6%)

10 (16.4%)

 

 Bicycle

14 (11.2%)

8 (12.5%)

6 (9.8%)

 

 Pedestrian

15 (12.0%)

5 (7.8%)

10 (16.4%)

 

Precipitation

10 (8.0%)

5 (7.8%)

5 (8.2%)

 

Penetrating

1 (0.8%)

1 (1.6%)

0 (0%)

 

Other

4 (3.2%)

3 (4.7%)

1 (1.6%)

 
  1. Quantitative variables are reported as median (interquartile range); categorical variables are reported as absolute values and rates. Quantitative variables are reported as median (interquartile range); categorical variables are reported as absolute values and rates. P values refer to comparisons between ISS > 15 and ISS < =15 subgroups, using Mann-Whitney U test for quantitative variables and Fisher’s exact test for rates. ISS Injury severity score, ICU Intensive care unit, RTS Revised trauma score, GCS Glasgow coma scale, SBP Systolic blood pressure, WBC White blood cells, bpm Breaths per minute (respiratory rate) or beats per minute (heart rate)
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