Table 1 Baseline characteristics of the ED patients
Number (Percent) or Median (Interquartile Range) | ||||||
|---|---|---|---|---|---|---|
Variable | Sepsis (n = 72) | Septic shock (n = 35) | P value | survivors (n = 81) | non-survivors (n = 26) | P value |
Age (Years) | 68(56.25–80) | 73(64–83) | 0.27 | 68(55.5–79) | 67.25(78.5–84.25) | 0.014 |
Gender (Males) Underlying diseases | 43(59.72%) | 21(60%) | 0.98 | 48(59.3%) | 21(60%) | 1.00 |
Hypertension | 25(34.7%) | 16(45.7%) | 0.296 | 26(32.1%) | 15(57.7%) | 0.036 |
Diabetes mellitus | 20(27.8%) | 10(28.6%) | 1.00 | 22(27.2%) | 8(30.8%) | 0.803 |
Coronary heart disease | 10(13.9%) | 17(48.6%) | <0.001 | 12(14.8%) | 15(57.7%) | <0.001 |
cerebral infarction | 12(16.7%) | 11(31.4%) | 0.131 | 15(18.5%) | 8(30.8%) | 0.271 |
Chronic pulmonary disease | 6(8.3%) | 5(14.3%) | 0.498 | 5(6.2%) | 6(23.1%) | 0.023 |
Autoimmune disease | 7(9.7%) | 5(14.3%) | 0.522 | 7(8.6%) | 5(19.2%) | 0.159 |
Previous surgical history | 10(13.9%) | 3(8.6%) | 0.539 | 11(13.6%) | 2(7.7%) | 0.730 |
Infection site | ||||||
Respiratory tract infection | 29(40.3%) | 28(80%) | <0.001 | 34(42%) | 23(88.5%) | <0.001 |
Urinary tract infection | 22(30.6%) | 3(8.6%) | 0.014 | 24(29.6%) | 1(3.8%) | 0.007 |
Gastrointestinal infection | 7(9.7%) | 3(8.6%) | 1.00 | 9(11.1%) | 1(3.8%) | 0.445 |
Hepatobiliary system infection | 7(9.7%) | 4(11.4%) | 0.747 | 9(11.1%) | 2(7.7%) | 1.000 |
skin infection | 4(5.6%) | 4(11.4%) | 0.434 | 5(6.2%) | 3(11.5%) | 0.399 |
intracranial infection | 0 | 1(2.9%) | 0.327 | 1(1.2%) | 0 | 1.000 |
Unknown origin | 8(11.1%) | 1(2.9%) | 0.266 | 8(9.9%) | 1(3.8%) | 0.449 |
Bloodstream infection | 21(29.2%) | 7(20%) | 0.357 | 24(29.6%) | 4(15.4) | 0.202 |
CRRT | 1(1.4%) | 7(20%) | 0.002 | 8(9.9%) | 5(19.2%) | 0.002 |
Mechanical ventilation | 3(4.2%) | 23(65.7%) | <0.001 | 8(9.9%) | 18(69.2%) | <0.001 |
Vasopressor use | 6(8.3%) | 29(82.9%) | <0.001 | 14(17.3%) | 21(80.8%) | <0.001 |
SOFA | 2 (2–3) | 10 (8–12) | <0.001 | 2(2–4) | 9(7–12.25) | <0.001 |
AKI | 29(40.3%) | 25(71.4%) | 0.004 | 37(45.7%) | 17(65.4%) | 0.114 |
SCM | 16(22.2%) | 24(68.6%) | <0.001 | 21(25.9%) | 19(73.1%) | <0.001 |
WBC(a109/L) | 10.67(6.74–15.49) | 12.62(8.65–14.77) | 0.150 | 10.59(6.74–15.33) | 13.01(11.36–14.87) | 0.028 |
Hb(g/L) | 122(111–135.75) | 119(94–139) | 0.834 | 125(111.5–137) | 106(81.75–138.25) | 0.062 |
Plt(a109/L) | 177(122.75–225.75) | 149(71–210) | 0.449 | 152(110–220) | 187.5(78.5–235) | 0.237 |
PCT (ng/ml) | 4.24(0.90–13.35) | 7.21(1.09–45.42) | 0.632 | 4.63(1.02–15.59) | 2.31(0.79–27.64) | 0.865 |
CRP (mg/L) | 139.49(72.50–200) | 133.82(41.69–200) | 0.835 | 142.43(68.97–200) | 118.29(53.18–189.76) | 0.647 |
Lactate (mmol/L) | 1.90(1.40–2.80) | 2.80(2.30–5.42) | <0.001 | 1.96(1.40–2.98) | 2.75(2.38–4.78) | 0.001 |
mtDNA (copies/ul) | 59,945(13274–95,319) | 134,252(70215–203,184) | 0.001 | 63,025(17031–98,401) | 165,291(89919–272,228) | 0.001 |
28-d mortality | 2(2.8%) | 24(68.6%) | <0.001 | |||
90-d mortality | 5(6.9%) | 26(74.3%) | <0.001 | |||