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Table 3 Patients charactreristics in leucine enriched and standard BCAA dietary supplements

From: Quick and effective improvement of leucine enriched dietary supplement on malnutrition in acute stroke patients receiving enteral tube feeding

Case

GCS on admission

Diagnosis

Medical history

BMI

BW

Cre on admission

eGFR on admission

T-CHO on admission

TG on admission

mRS before stroke

EN (1 pack)

Protein intake by EN (g/day)

Protein intake by EN (g/kg/day)

Calorie intake (/day)

Target calorie (/day)

Outcome

Hospitalization (days)

Leucine enriched BCAA dietary supplement

 1

7

Cardioembolic stroke

Af, HT, Asthma

23.3

62

0.73

58.15

201

94

0

Impact (250 k, P14g)

70

1.1

1250

1515

Discharge

8

 2

13

Ischemic stroke (Large vessel occlusion)

HT, DM, ASO, post-surgery of rectal cancer

24.5

65

0.78

74.03

241

203

0

Peptamen AF (300 k, P19g)

75.6

1.2

1200

1434

Discharge

15

 3

15

Intracerebral hemorrhage (hypertensive)

HT, CRF (HD), hypothroidism

18.4

50

6.96

6.56

97

58

3

Renalen MP (400 k, P14g)

42

0.8

1200

1239

Discharge

11

 4

9

Intracerebral hemorrhage (hypertensive)

HT, ASO

21.8

49

1.04

52.47

174

56

3

Peptamen AF (300 k, P19g)

75.6

1.5

1200

1122

Discharge

14

 5

11

Cardioembolic stroke

HT, DM, CKD, Anemia

18.3

44

1.75

21.30

206

101

5

Renalen MP (400 k/P)

42

1.0

1200

1328

Discharge

12

 6

12

Cardioembolic stroke

Af, HT, DM, MVR

17.6

45

0.74

57.51

139

42

0

Peptamen AF (300 k, P19g)

75.6

1.7

1200

1344

Discharge

8

 7

7

Intracerebral hemorrhage (hypertensive)

HT, DL, CKD

13.9

30

0.71

56.44

286

65

3

MEIN (200 k, P10g)

60

2.0

1200

1005

Discharge

12

 8

3

Intracerebral hemorrhage (hypertensive)

Paf, HT, DM, Dementia, DVT

23.5

64

0.68

80.80

159

87

2

MEIN (200 k, P10g)

70

1.1

1400

1803

In-hospital death

8

 9

9

Ischemic stroke (Large vessel occlusion)

HT, DL, CKD, CHF

20.6

44

0.86

45.76

256

124

5

MEIN (200 k, P10g)

60

1.4

1200

1081

Discharge

14

 10

5

Intracerebral hemorrhage (hypertensive)

HT, DL, ASO, OMI (post-CABG), post-CAS

23.4

58

0.92

50.61

137

167

0

MEIN (200 k, P10g)

70

1.2

1400

1356

Discharge

10

 11

14

Ischemic stroke (Large vessel occlusion)

Af, HT, DM, DL, CRF, post-CABG, stent gradt for AAA

22.3

57

9.35

4.75

119

92

3

MEIN (200 k, P10g)

70

1.2

1400

1521

Discharge

17

 12

15

Cardioembolic stroke

Af, HT, left IC occlusion, breast cancer

25.7

57

0.59

71.84

216

65

0

MEIN (200 k, P10g)

70

1.2

1400

1563

Discharge

13

 13

7

Cardioembolic stroke

Af, HT, DL, IGT, Lung cancer, DVT, intracerebral aneurysm (unruptured)

23.5

55

0.76

56.39

158

102

0

Renalen MP (400 k, P14g)

42

0.8

1200

1293

In-hospital death

21

 14

14

Cardioembolic stroke

Paf

15.8

37

0.70

59.18

188

128

3

Peptamen AF (300 k, P19g)

75.6

2.0

1200

1063

Discharge

16

 15

8

Cardioembolic stroke

HT, right MCA stenosis

17.3

39

0.83

47.72

210

58

4

MEIN (200 k, P10g)

50

1.3

1000

943

Discharge

8

Median

9

  

21.8

50

0.78

56.4

188

92

3

 

70

1.2

1200

1328

 

12

Standard BCAA dietary supplement

 1

7

Ischemic stroke (Large vessel occlusion)

HT, DL, Paf

22.6

67

0.77

71.7

206

36

0

Impact (250 k, P14g)

70

1.0

1500

1628

Discharge

10

 2

13

Cardioembolic stroke

Af, HT, DM, Obesity, OCI

25.8

62

0.49

92.8

161

63

0

Peptamen AF (300 k, P19g)

75.6

1.2

1200

1321

Discharge

11

 3

14

Cardioembolic stroke

DM, OCI, AAA

16.5

45

0.65

91.1

159

105

2

Peptamen AF (300 k, P19g)

94.5

2.1

1500

1350

Discharge

14

 4

3

Cardioembolic stroke

HT, DM, HL, CABG,OCI, Basedow,

19.5

44

1.15

35.2

133

90

4

MEIN (200 k, P10g)

60

1.4

1200

1077

Discharge

8

 5

4

Cardioembolic stroke

Paf, HT, HL, DM

23.8

50

0.9

44.4

235

116

2

Impact (250 k, P14g)

56

1.1

1000

1036

Discharge

9

 6

13

Ischemic stroke (small vessel occlusion)

HT, AP, OCI, Dementia, DVT

22.0

55

0.68

60.9

241

85

4

MEIN (200 k, P10g)

60

1.1

1200

1286

Discharge

10

 7

12

Intracerebral hemorrhage (hypertensive)

HT, DVT

20.0

45

0.71

58.1

205

133

3

MEIN (200 k, P10g)

50

1.1

1000

1258

Discharge

10

 8

8

Cardioembolic stroke

Af, HT, OCI, DL

24.0

54

0.47

92.4

206

113

4

Peptamen AF (300 k, P19g)

75.6

1.4

1200

1340

Discharge

9

 9

11

Intracerebral hemorrhage (hypertensive)

HT

14.5

39

0.48

91.7

182

34

0

Impact (250 k, P14g)

56

1.4

1000

1054

Discharge

9

 10

8

Ischemic stroke (Large vessel occlusion)

HT, DM, DL

21.8

63

0.6

97.5

223

98

4

Peptamen AF (300 k, P19g)

94.5

1.5

1500

1590

Discharge

18

 11

3

Cardioembolic stroke

Paf, HT,LC

15.9

43

1.68

30.8

126

 

1

Renalen MP (400 k, P14g)

35

0.8

1000

1111

In-hospital death

10

 12

9

Ischemic stroke (Large vessel occlusion)

HT,DM,OCI, DL, Dydrocephalus, ASO

18.7

42

0.72

56.8

189

171

5

Peptamen AF (300 k, P19g)

75.6

1.8

1200

1238

Discharge

7

 13

10

Ischemic stroke (small vessel occlusion)

HT, SAH

15.0

36

0.52

83.7

163

96

4

Peptamen AF (300 k, P19g)

75.6

2.1

1200

1099

Discharge

7

 14

13

Cardioembolic stroke

HT, HL, DM

18.1

48

0.92

60.6

159

75

0

Peptamen AF (300 k, P19g)

75.6

1.6

1200

1218

Discharge

22

Median

9.5

  

19.7

46.5

0.70

66.3

186

96

3

 

72.8

1.4

1200

1248

 

10

  1. BCAA branced-chain amino acids, P protein, GCS Glasgow Coma Scale, BMI body mass index (kg/m2), BW body weight (kg), Cre serum creatinine (mg/dl), eGFR estimated Glomerular Filtration Rate (mL/min/1.73 m2), T-CHO total cholesterol (mg/dl), TG triglyceride (mg/dl), mRS modified Rankin scale, EN enteral nutrient, k kcal, Af atrial filtration, HT hypertension, DM diabetes mellitus, CRF chronic renal failure, HD hemodyalysis, ASO arteriosclerosis obliterans, CKD chronic kidney disease, MVR mitral valve replacement, DL dyslipidemia, DVT deep venous thrombosis, CHF chronic heart failure, OMI old myocardial infarction, Paf paroxysmal af, CABG coronary aorta bypass surgery, CAS carotid artery stenting, AAA abdominal aorta aneurysm, IC internal carotid artery, IGT impaired glucose tolerance, MCA middle cerebral artery