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Table 1 Patients’ baseline characteristics

From: A retrospective study of sepsis-associated encephalopathy: epidemiology, clinical features and adverse outcomes

 

All patients n = 291

SAE

n = 127

non-SAE

n = 164

P

Age (years), median

59 [45, 72]

64 [48, 76]

55 [43, 68]

< 0.01*

Sex (%)

 Male

213 (73.2)

90 (70.9)

123 (75.0)

0.430

 Female

78 (26.8)

37 (29.1)

41 (25.0)

Underlying diseases (%)

 Hypertension

75 (25.8)

41 (32.3)

34 (20.7)

0.025*

 Diabetes

40 (13.7)

23 (18.1)

17 (10.4)

0.057

 COPD

28 (9.6)

10 (7.9)

18 (11.0)

0.374

 CHF

37 (12.7)

19 (15.0)

18 (11.0)

0.312

 CHD

12 (4.1)

4 (3.1)

8 (4.9)

0.462

 CKD

17 (5.8)

7 (5.5)

10 (6.1)

0.833

 Malignant tumor

44 (15.1)

22 (17.3)

22 (13.4)

0.356

 Immune diseases

4 (1.4)

1 (0.8)

3 (1.8)

0.803

 Others

26 (8.9)

13 (10.2)

13 (7.9)

0.493

Disease severity (median)

 SOFA score

5 [2, 7]

7 [5, 10]

3 [1, 5]

< 0.01*

 APACHE II score

11 [8, 15]

15 [12, 19.5]

9 [6, 11]

< 0.01*

Outcome

 Hospital LOS (median)

20 [11, 30]

19 [9, 28]

21 [13, 36]

0.143

 28-day mortality (%)

77 (26.5)

54 (42.5)

21 (12.8)

< 0.01**

  1. SAE sepsis-associated encephalopathy, COPD chronic obstructive pulmonary disease, CHF chronic heart failure, CHD chronic hepatic disease, CKD chronic kidney disease, SOFA sequential organ failure assessment, APACHE II acute physiology, age and chronic health evaluation II, LOS length of stay
  2. *Statistical analysis using Mann Whitney test, **Statistical analysis using Fisher’s exact probability method