|
Univariate Logistic Regression for INR Goal Met
|
|
PCC4
|
14.44 (3.80–54.93)
|
< 0.001
|
|
Female
|
3.48 (1.36–8.90)
|
0.009
|
|
Age
|
1.00 (0.98–1.03)
|
0.85
|
|
Weight (kg)
|
1.00 (0.98–1.02)
|
0.71
|
|
Dose (per 500 unit vial)
|
1.23 (0.92–1.63)
|
0.16
|
|
Bleed type
|
|
Other
|
Ref.
| |
|
Intracranial
|
2.17 (0.70–6.68)
|
0.18
|
|
Gastrointestinal
|
2.00 (0.45–8.94)
|
0.36
|
|
Initial INR
|
0.78 (0.61–1.01)
|
0.06
|
|
FFP units used
|
1.05 (0.67–1.63)
|
0.84
|
|
Time from pre- to post-PCC INR (in hours)
|
1.28 (1.08–1.53)
|
0.005
|
|
Survivors
|
1.12 (0.42–3.00)
|
0.82
|
|
Length of stay, all
|
0.95 (0.88–1.03)
|
0.22
|
|
Length of stay, survivors
|
0.94 (0.85–1.05)
|
0.27
|
|
Thromboembolism, yes
|
0.43 (0.10–1.79)
|
0.25
|
|
PS Adjusted Logistic Regression
|
AOR (95% CI)
| |
|
PCC4
|
10.55 (2.17–51.24)
|
< 0.001
|
|
Linear Regression
|
Coefficient (95% CI)
| |
|
Intercept (mean INR change PCC3)
|
1.64 (1.22–2.07)
|
< 0.001
|
|
mean INR change PCC4
|
0.91 (0.12–1.70)
|
0.03
|
|
Intercept (post-PCC INR PCC3)
|
1.90 (1.69–2.12)
|
< 0.001
|
|
post-PCC INR PCC4
|
−0.51 (−0.91- -0.12)
|
0.01
|
|
PS Adjusted Linear Regression
|
Coefficient (95% CI)
| |
|
Intercept (mean INR change PCC3)
|
1.39 (0.89–1.89)
|
< 0.001
|
|
mean INR change PCC4
|
0.30 (−0.74–1.33)
|
0.56
|
|
Intercept (post-PCC INR PCC3)
|
1.98 (1.73–2.23)
|
< 0.001
|
|
post-PCC INR PCC4
|
−0.45 (− 0.85- -0.19)
|
0.21
|
