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Table 1 Summary of model parameters

From: Cost-effectiveness of out-of-hospital continuous positive airway pressure for acute respiratory failure: decision analytic modelling using data from a feasibility trial

Parameter Mean Distribution or 95% CI Source
Baseline risks
 Risk of mortality 0.257 Beta (9,26) ACUTE
 Risk of intubation 0.034 Beta (1,28) ACUTE
OR for prehospital CPAP
Base case scenario (effectiveness parameters from ACUTE)
  Log (Mortality OR) 0.145 Normal (0.145, 0.521) ACUTE
  Log (Intubation OR) 0.591 Normal (0.591, 1.403) ACUTE
Scenario using effectiveness parameters from NMA
  Log (Mortality OR) −0.916 Samples ACUTE, HTA meta-analysis [2]
  Log (Intubation OR) −1.050 Samples ACUTE, HTA meta-analysis [2]
Life expectancy of patients
 Lifetime years 2.67 years Normal (2.67, 0.16) 3CPO trial [12], Clinical opinion
Health related quality of life
 Utility 0.6 Beta (640,425) 3CPO trial [12], Clinical opinion
Costs (in £)
 Prehospital CPAP £33 Normal (£33, £3.3) O-Two/SP [13], WMAS, Expert opinion
 Hospitalisation £3200 Gamma (80,40) NHS Reference Costs [14]
 Intubation £3600 Gamma (90, 40) HCHS index [15], Clinical opinion
 Annual costs £6000 Gamma (60, 100) 3CPO trial [12], HCHS index [15], Clinical opinion
  1. HCHS Hospital and Community Health Services, WMAS West Midland Ambulance Service.