Prognostic value of neutrophil- lymphocyte count ratio (NLCR) among adult ICU patients in comparison to APACHE II score and conventional inflammatory markers: a multi center retrospective cohort study

Table 2 Characteristics of infected and non-infected patients

	Non-infective n = 148	Infective
	Non-infective n = 148	Pneumonia n = 208	Bacteremia n = 19	Peritonitis n = 23	Intra-cranial Infection n = 15	Other Infections n = 15	Total n = 280
Age (year)	67.6 ± 17.7	70.7 ± 18.3	68.5 ± 19.3	63 ± 18.5	60.5 ± 14.7	79.5 ± 13.8^*	69.9 ± 18.3
Gender (M/F)	81/67	157/51	11/8	14/9	11/4	11/4	204/76
Temperature abnormalities, n, (%)	58 (39.2)	107 (51.4)^*	13 (68.4)^*	14 (60.9)	7 (46.7)	7 (46.7)	147 (52.5)^*
WBC abnormalities, n, (%)	37 (25.0)	62 (29.8)	8 (42.1)	11 (47.8)^*	8 (53.3)^*	3 (20.0)	92 (32.9)
NE abnormalities, n, (%)	105 (70.9)	141 (67.8)	10 (52.6)	23 (100)^**	13 (86.7)	9 (60.0)	196 (70.0)
APACHE II score	18.3 ± 5.2	21.3 ± 6.1^***	21.5 ± 8.4^*	20.5 ± 6.9	18.2 ± 6.2	21.6 ± 4.3^*	21.1 ± 6.2^***
NLCR	11.7 ± 13.5	11.3 ± 11.7	9.8 ± 8.5	17 ± 31.1	14.9 ± 11.4	10.8 ± 11.1	11.9 ± 14.1
PCT (ng/ml)	0.9 ± 2.5	4.3 ± 14.6^*	5.3 ± 10.1	21.3 ± 35.1^***	0.8 ± 1.3	1 ± 1.3	5.4 ± 16.9^***
CRP (mg/ml)	46.6 ± 52.1	72 ± 78.5^*	42.9 ± 40.9	117.4 ± 99.9^***	70.8 ± 64.9	59.5 ± 68.6	73.4 ± 78.7^***
Blood lactate (mmol/l)	1.4 ± 1.3	1.6 ± 1.1	2.4 ± 3.2	2 ± 1.1	1.6 ± 0.9	1.7 ± 0.9	1.8 ± 1.3^*
Surgery, n, (%)	41 (27.7)	47 (22.6)	7 (36.8)	12 (52.2)^**	11 (73.7)^***	0 (0)^*	77 (27.5)

Data were expressed as number (percentage) of patients or mean ± standard deviation. *p < 0.05,**p < 0.01, ***p < 0.001 vs non-infective group. Temperature abnormality: temperature < 36 °C or > 38 °C; WBC abnormalities: WBC < 4 × 10 ^ 9 / L or > 12 × 10 ^ 9 / L; NE abnormality: neutrophil count ratio < 40% or > 75%

ISSN: 1471-227X