BMC Emergency Medicine

Table 2 Correlation between EG degradation indicators and organ function in trauma group on admission

From: Endothelial glycocalyx degradation is associated with early organ impairment in polytrauma patients

Characteristic	Serum SDC1		Serum HS
Characteristic	r	P value	r	P value
Demographic
Age	0.209	0.169	−0.009	0.956
BMI	−0.141	0.356	−0.024	0.875
Score system
GCS	0.020	0.897	−0.312	0.037
ISS	0.380	0.010	0.320	0.032
SOFA	0.267	0.076	0.296	0.048
Liver function
TBIL	−0.089	0.562	0.065	0.670
ALB	−0.652	< 0.001	−0.373	0.012
Kidney function
BUN	0.558	< 0.001	0.262	0.082
Cr	0.603	< 0.001	0.388	0.009
Respiratory function
PaO₂	−0.318	0.033	−0.232	0.125
PaO₂/FiO₂ ratio	−0.458	0.006	−0.396	0.007
EVLW	0.515	< 0.001	0.344	0.021
Metabolism system
pH	−0.513	< 0.001	−0.367	0.014
HCO₃⁻	−0.471	0.001	−0.209	0.169
Lac	0.507	< 0.001	0.377	0.011
Cardiovascular
NT-pro BNP	0.379	0.010	0.296	0.049
Tn I	0.289	0.054	0.289	0.054
Mb	0.481	0.001	0.455	0.002
Coagulation
Hb	−0.468	0.001	−0.263	0.080
PLT	−0.314	0.036	−0.272	0.071
Ca²⁺	−0.545	< 0.001	−0.398	0.007
Fib	−0.006	0.970	0.037	0.809
PT	0.502	< 0.001	0.511	< 0.001
APTT	0.592	< 0.001	0.600	< 0.001
AT-III	−0.752	< 0.001	−0.522	< 0.001
D-dimer	−0.063	0.683	0.122	0.424
Inflammation
WBC	−0.059	0.700	0.148	0.331
PCT	0.437	0.003	0.285	0.057
IL-6	0.384	0.009	0.326	0.029
TNF-α	0.531	< 0.001	0.390	0.008

Abbreviations: EG endothelial glycocalyx; SDC1 syndecan-1; HS heparan sulfate; BMI body mass index; GCS Glasgow coma score; ISS injury severity score; SOFA sequential organ failure assessment; TBIL total bilirubin; ALB albumin; BUN blood urea nitrogen; Cr creatinine; EVLW extravascular lung water; Lac lactic acid; NT-pro BNP N-terminal pro-B-type natriuretic peptide; Tn I troponin I; Mb myoglobin; Hb hemoglobin; PLT platelet; Fib fibrinogen; PT prothrombin time; APTT activated partial thromboplastin time; AT-III anti-thrombin; WBC white blood cell; PCT procalcitonin; IL-6 interleukin-6; TNF-α tumor necrosis factor

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ISSN: 1471-227X

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