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Table 4 Comparison of the predict value of SDC1, HS, ISS and SOFA on early AKI, TIC, and 28-day mortality

From: Endothelial glycocalyx degradation is associated with early organ impairment in polytrauma patients

 

AKI within 48 h

TIC within 48 h

28-day mortality

AUC

95% CI

P value

AUC

95% CI

P value

AUC

95% CI

P value

SDC1

0.838

0.720–0.957

< 0.001

0.700

0.514–0.885

0.038

0.764

0.543–0.984

0.021

HS

0.671

0.488–0.854

0.059

0.786

0.650–0.922

0.003

0.721

0.506–0.937

0.052

ISS

0.697

0.541–0.854

0.030

0.642

0.464–0.819

0.140

0.662

0.444–0.880

0.154

SOFA

0.635

0.463–0.806

0.138

0.662

0.506–0.818

0.091

0.583

0.406–0.760

0.467

  1. Abbreviations: AKI acute kidney injury; TIC trauma induced coagulopathy; SDC1 syndecan-1; HS heparan sulfate; BMI body mass index; ISS injury severity score; SOFA sequential organ failure assessment
  2. AUC denotes area under the curve