Table 1 Characteristics of patients with fever for each period
Characteristic | Control period (n = 5335) | Exposure period (n = 7423) | P-value |
|---|---|---|---|
Age, years | |||
Median (IQR) | 8 (3–11) | 10 (4–33) | < 0.001 |
Category, n (%) | < 0.001 | ||
0–14 | 3147 (59.0) | 4152 (55.9) | |
15–64 | 2112 (39.6) | 3089 (41.6) | |
≥ 65 | 76 (1.4) | 182 (2.5) | |
Male sex, n (%) | 2765 (48.2) | 3839 (48.3) | 0.90 |
Month, n (%) | < 0.001 | ||
December | 523 (9.8) | 1683 (22.7) | |
January | 1704 (31.9) | 2052 (27.6) | |
February | 1243 (23.3) | 2062 (27.8) | |
March | 900 (16.9) | 1057 (14.2) | |
April | 968 (18.1) | 570 (7.7) | |
Diagnosis, n (%) | |||
Upper respiratory tract infection | 4555 (85.4) | 5875 (79.1) | < 0.001 |
Influenza | 1916 (35.9) | 2119 (28.5) | < 0.001 |
Streptococcal infection | 78 (1.5) | 161 (2.2) | < 0.001 |
Tonsillitis | 191 (3.6) | 254 (3.4) | 0.63 |
Sinusitis | 15 (0.3) | 34 (0.5) | 0.11 |
COVID-19 | 0 (0.0) | 6 (0.1) | 0.038 |
Pneumonia | 38 (0.7) | 61 (0.8) | 0.49 |
Asthma | 48 (0.9) | 40 (0.5) | 0.021 |
Otitis media | 72 (1.4) | 106 (1.4) | 0.71 |
Urinary tract infection | 24 (0.4) | 67 (0.9) | < 0.001 |
Gastroenteritis | 773 (14.5) | 1064 (14.3) | 0.22 |
Other abdominal disease | 35 (0.7) | 82 (1.1) | < 0.001 |
Other | 138 (2.6) | 427 (5.7) | < 0.001 |
Comorbidities, n (%) | |||
Hypertension | 28 (0.5) | 65 (0.9) | 0.019 |
Diabetes mellitus | 21 (0.4) | 40 (0.5) | 0.24 |
Hyperlipidemia | 10 (0.2) | 17 (0.2) | 0.61 |
Gout | 3 (0.1) | 5 (0.1) | 0.80 |
Chronic lung disease | 178 (3.3) | 230 (3.1) | 0.45 |
Heart failure | 0 (0) | 5 (0.1) | 0.06 |
Liver disease | 6 (0.1) | 14 (0.2) | 0.27 |
Cerebral infarction | 8 (0.2) | 14 (0.2) | 0.60 |
Cancer | 30 (0.6) | 59 (0.8) | 0.12 |
Collagen disease | 5 (0.1) | 6 (0.1) | 0.27 |
Dementia | 3 (0.1) | 7 (0.1) | 0.45 |