Table 3 Distribution of bleeding characteristics of all included hemorrhages
DOAC (n = 158) | VKA (n = 419) | Total (n = 577) | p | |
|---|---|---|---|---|
Location, [n (%)]a | ||||
Epistaxis | 14 (8.9) | 46 (11.0) | 60 (10.4) | 0.457 |
Oral | 2 (1.3) | 8 (1.9) | 10 (1.7) | 0.597 |
Intracranial | 23 (14.6) | 94 (22.4) | 117 (20.3) | 0.036 |
Thorax | 5 (3.2) | 8 (1.9) | 13 (2.3) | 0.365 |
Extremity | 1 (0.6) | 0 (0.0) | 1 (0.2) | 0.103 |
Gastrointestinal | 55 (34.8) | 119 (28.4) | 174 (30.2) | 0.135 |
Intraabdominal | 3 (1.9) | 5 (1.2) | 8 (1.4) | 0.518 |
Retroperitoneal | 1 (0.6) | 10 (2.4) | 11 (1.9) | 0.170 |
Superficial | 26 (16.5) | 77 (18.4) | 103 (17.9) | 0.591 |
Intraocular | 0 (0.0) | 2 (0.5) | 2 (0.3) | 0.384 |
Intraarticular | 1 (0.6) | 6 (1.4) | 7 (1.2) | 0.434 |
Intraspinal | 1 (0.6) | 1 (0.2) | 2 (0.3) | 0.472 |
Intramuscular | 4 (2.5) | 25 (6.0) | 29 (5.0) | 0.092 |
Gross haematuria | 18 (11.4) | 34 (8.1) | 52 (9.0) | 0.220 |
Haemoptysis | 3 (1.9) | 7 (1.7) | 10 (1.7) | 0.851 |
Other location | 22 (13.9) | 41 (9.8) | 63 (10.9) | 0.155 |
Extent of bleeding, [n (%)] | ||||
Haemorrhagic shock | 10 (6.3) | 21 (5.0) | 31 (5.4) | 0.531 |
Major bleeding | 67 (42.4) | 183 (43.7) | 250 (43.3) | 0.784 |