Skip to main content

Table 1 Baseline characteristics according to the antibiotics prescribed before and after propensity score matching

From: Antibiotic prescription consistent with guidelines in emergency department is associated with 30-day survival in severe community-acquired pneumonia

  Before propensity score matching After propensity score matching
Guideline-concordant antibiotics (N = 359) Guideline-discordant antibiotics (N = 271) SD Guideline-concordant antibiotics (N = 255) Guideline-discordant antibiotics (N = 255) SD
Age 74.63 (11.56) 76.85 (11.66) 0.191 75.75 (11.16) 76.81 (11.86) 0.092
Sex (Male) 245 (68.2) 179 (66.1) 0.047 170 (66.7) 167 (65.5) 0.025
Comorbidities
 Diabetes mellitus 114 (31.8) 83 (30.6) 0.024 83 (32.5) 80 (31.4) 0.025
 Hypertension 190 (52.9) 132 (48.7) 0.084 129 (50.6) 125 (49.0) 0.031
 Chronic obstructive lung disease 43 (12.0) 23 (8.5) 0.115 24 (9.4) 23 (9.0) 0.014
 Congestive heart failure 12 (3.3) 6 (2.2) 0.068 8 (3.1) 5 (2.0) 0.075
 Chronic kidney disease 43 (12.0) 35 (12.9) 0.028 34 (13.3) 34 (13.3) < 0.001
 Chronic liver disease 30 (8.4) 13 (4.8) 0.144 15 (5.9) 13 (5.1) 0.034
 Neoplastic diseases 109 (30.4) 69 (25.6) 0.107 67 (26.3) 67 (26.3) < 0.001
 Cerebrovascular disease 104 (29.0) 101 (37.3) 0.177 84 (32.9) 91 (35.7) 0.058
Initial hemodynamic variables
 Mean arterial pressure (mmHg) 88.51 (21.97) 87.89 (21.03) 0.029 87.53 (21.72) 87.76 (21.28) 0.011
 Heart rate (beat/min) 107.58 (25.38) 104.27 (25.47) 0.130 104.84 (25.10) 104.76 (25.74) 0.003
 Respiratory rate (breath/min) 24.89 (7.01) 25.17 (7.08) 0.040 24.82 (7.03) 25.15 (7.02) 0.046
 Body temperature (°C) 37.39 (1.16) 37.15 (1.11) 0.213 37.23 (1.15) 37.19 (1.10) 0.034
Laboratory results
 White blood cell (103/μL) 11.26 (7.71) 12.59 (7.71) 0.172 12.14 (8.01) 12.40 (7.58) 0.033
 Hemoglobin (g/dL) 11.56 (2.31) 11.39 (2.29) 0.074 11.38 (2.41) 11.45 (2.31) 0.026
 Platelet (103/μL) 211.66 (110.39) 218.59 (117.09) 0.061 214.47 (110.81) 216.12 (116.32) 0.015
 BUN (mg/dL) 32.83 (22.78) 38.66 (26.56) 0.236 35.98 (24.99) 38.00 (25.92) 0.079
 Creatinine (mg/dL) 1.58 (1.59) 1.69 (1.65) 0.069 1.69 (1.80) 1.69 (1.68) 0.003
 Albumin (g/dL) 3.08 (0.55) 3.00 (0.63) 0.138 3.05 (0.55) 3.00 (0.63) 0.072
 CRP (mg/dL) 14.00 (9.11) 12.58 (9.04) 0.157 12.77 (8.68) 12.69 (9.10) 0.008
PSI score 132.19 (34.63) 140.03 (38.26) 0.215 136.24 (35.43) 139.08 (38.75) 0.076
Multidrug-resistant pathogens isolateda 32 (8.9) 42 (15.5) 0.202 30 (11.8) 36 (14.1) 0.070
  1. Data are expressed as mean (standard deviation) or n (%) as appropriate. BUN blood urea nitrogen, CRP C-reactive protein, PSI pneumonia severity index
  2. aMultidrug-resistant pathogens includes Pseudomonas aeruginosa, Methicillin-Resistant Staphylococcus aureus, and ESBL-producing Gram-negative organisms
  3. The standardized difference was calculated to compare variables before and after the propensity score matching. Imbalance was defined as the standardized difference greater than 0.10