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Table 1 Baseline and injury characteristics of the study population

From: Timely intubation with early prediction of respiratory exacerbation in acute traumatic cervical spinal cord injury

 

Overall

(n = 58)

RE group

(n = 13)

Control group

(n = 45)

Unadjusted OR (95% CI)

P-value

Age, median [IQR], y

70 [65–75]

75 [68–80]

70 [64–74]

 

0.1759

> 65 y, n (%)

42 (72.4)

11 (84.6)

31 (68.8)

2.38 (0.48–12.72)

0.3183

Male sex, n (%)

46 (79.3)

12 (92.3)

34 (75.6)

0.25 (0.03–2.21)

0.2640

Body mass index, median [IQR]

22 [20–24]

22 [21–25]

21 [20–25]

 

0.0572

> 24, n (%)

13 (22.4)

3 (23.1)

10 (22.2)

1.05 (0.24–4.56)

1.0000

CCI, median [IQR]

0 [0–1]

1 [0–3]

0 [0–1]

 

0.1020

> 1, n (%)

11 (18.9)

5 (38.4)

6 (13.3)

4.06 (0.99–16.63)

0.1010

Pulmonary centrilobular emphysema, n (%)

14 (24.1)

3 (23.1)

11 (24.4)

0.92 (0.21–3.98)

1.0000

Cervical OPLL, n (%)

13 (22.4)

3 (23.1)

10 (22.2)

1.05 (0.24–4.56)

1.0000

DISH, n (%)

8 (13.8)

2 (15.4)

6 (13.3)

1.18 (0.21–6.69)

1.0000

Initial GCS, median [IQR]

15 [14–15]

14 [13–15]

15 [14–15]

 

0.0827

< 15, n (%)

20 (34.4)

7 (53.8)

13 (28.8)

2.87 (0.81–10.19)

0.1112

Initial bradycardia, n (%)

18 (31.1)

5 (38.5)

13 (28.9)

1.53 (0.42–5.58)

0.5156

Initial hypotension, n (%)

14 (24.1)

4 (30.8)

10 (22.2)

1.55 (0.39–6.13)

0.7138

Fall, n (%)

36 (62.1)

9 (69.2)

27 (60.0)

1.50 (0.40–5.61)

0.7475

Motor vehicle accident, n (%)

18 (31.1)

2 (15.4)

16 (35.6)

0.32 (0.06–1.67)

0.3068

ISS, median [IQR]

17 [16–22]

25 [18–26]

17 [16–18]

 

0.0023*

ISS > 25, n (%)

14 (24.1)

7 (53.8)

7 (15.5)

6.33 (1.63–24.57)

0.0088*

ISS > 16, n (%)

53 (91.3)

13 (100)

40 (88.9)

N/A

0.5773

Abbreviated Injury Scale for chest

 1, n (%)

1 (1.7)

0

1 (2.2)

N/A

1.0000

 2, n (%)

2 (3.4)

1 (7.7)

1 (2.2)

3.66 (0.21–63.03)

0.4010

 3, n (%)

2 (3.4)

0

2 (4.4)

N/A

1.0000

 4, n (%)

1 (1.7)

0

1 (2.2)

N/A

1.0000

 5

0

0

0

  

 Lung injury, n (%)

2 (3.4)

1 (7.7)

1 (2.2)

3.66 (0.21–63.03)

0.4010

 Bony thorax injury, n (%)

1 (1.7)

0

1 (2.2)

N/A

1.0000

 Thoracic vertebral fracture, n (%)

4 (7.0)

1 (7.7)

3 (6.7)

1.16 (0.11–12.26)

1.0000

AIS grade

 A, n (%)

9 (15.5)

4 (30.8)

5 (11.1)

3.55 ((0.79–15.84)

0.1025

 B, n (%)

18 (31.1)

7 (53.9)

11 (24.4)

3.61 (0.99–13.03)

0.0851

 C, n (%)

17 (29.3)

2 (15.4)

15 (33.3)

0.36 (0.07–1.85)

0.3068

 D, n (%)

14 (24.1)

0

14 (31.1)

N/A

0.0269*

 Motor-complete injury, n (%)

27 (46.6)

11 (84.6)

16 (35.6)

9.96 (1.96–50.65)

0.0034*

Neurological CSCI level

 C3, n (%)

12 (20.7)

1 (7.7)

11 (24.4)

0.25 (0.03–2.21)

0.2640

 C4, n (%)

10 (17.2)

4 (30.8)

6 (13.3)

2.88 (0.67–12.41)

0.2083

 C5, n (%)

22 (37.9)

7 (53.9)

15 (33.3)

2.33 (0.66–8.17)

0.2078

 C6, n (%)

14 (24.1)

1 (7.7)

13 (28.9)

0.21 (0.02–1.74)

0.1553

 Level of injury above C5, n (%)

22 (37.9)

5 (38.5)

17 (37.8)

1.03 (0.28–3.66)

1.0000

  1. OR odds ratio, CI confidence interval, IQR interquartile range, RE respiratory exacerbation, CCI Charlson Comorbidity Index, OPLL ossification of posterior longitudinal ligament, DISH diffuse idiopathic skeletal hyperostosis, GCS Glasgow Coma Scale, ISS Injury Severity Score, ASIA American Spinal Injury Association, AIS ASIA Impairment Scale, CSCI cervical spinal cord injury
  2. *Statistically significant at P < 0.05