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Table 1 Characteristics and clinical outcomes in patients with or without multiple organ dysfunction on Day2

From: Risk prediction of biomarkers for early multiple organ dysfunction in critically ill patients

 

MOD

(n = 96)

without MOD

(n = 65)

P value

Characteristics

 Age, years

70 (59–78)

72 (64–85)

0.145

 Male sex, n(%)

59 (61.5)

42 (64.6)

0.684

 Etiology of SIRS, (%)

  Infection

63 (65.6)

46 (70.8)

0.493

  Post-surgery

8 (8.3)

4 (6.2)

0.605

  Trauma

14 (14.6)

8 (12.3)

0.680

  Burn

1 (1.0)

0 (0.0)

0.409

  Acute pancreatitis

6 (6.3)

3 (4.6)

0.658

  Others

10 (10.4)

6 (9.2)

0.805

 APACHEII score on admission

29 (23–37)

19 (13–22)

<  0.001*

 qSOFA on admission

  

<  0.001*

  0

1

14

–

  1

33

29

–

  2

35

21

–

  3

26

1

–

 qSOFA≧2 on admission, n(%)

61 (64.2)

22 (33.8)

<  0.001*

 SOFA score on admission

  Total SOFA score

10 (7–13)

3 (2–5)

<  0.001*

  Respiration, (%)

72 (75.0)

23 (37.1)

<  0.001*

  Coagulation, (%)

29 (30.2)

4 (6.2)

<  0.001*

  Liver, (%)

14 (14.7)

4 (6.2)

0.092

  Cardiovascular, (%)

58 (60.4)

3 (4.6)

<  0.001*

  Central Nervous System, (%)

67 (69.8)

9 (13.8)

<  0.001*

  Renal, (%)

46 (47.9)

9 (13.8)

<  0.001*

Outcome

 In hospital 28 day mortality

16 (16.7)

2 (3.1)

0.007*

 ICU free days

13 (0–20)

26 (23–28)

<  0.001*

 Ventilator free days

16 (1–24)

28 (28–28)

<  0.001*

 RRT free days

25 (11–28)

28 (28–28)

<  0.001*

  1. MOD Multiple organ dysfunction, SIRS Systemic inflammatory response syndrome, APACHE Acute Physiology and Chronic Health Evaluation, qSOFA Quick Sequential Organ Failure Assessment, ICU Intensive care unit, RRT Renal replacement therapy
  2. Data are presented as median and interquartile range for continuous variables and exact number (%) for categorical variables. P-values were calculated using Pearson’s chi-square test or the Wilcoxon test. For APACHE II score, n = 93 with MOD and n = 37 without MOD