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Table 2 Blood levels of each biomarker in patients with or without multiple organ dysfunction on day 0,1,2

From: Risk prediction of biomarkers for early multiple organ dysfunction in critically ill patients

Day-0

All (n = 161)

MOD (n = 99)

without MOD (n = 62)

Interleukin-6, pg/ml, median (IQR)

371.7 (151.7–2471)

1111 (175.7–6204)

210.7 (87.34–554.18)

Procalcitonin, ng/ml, median (IQR)

2.19 (0.34–9.3)

5.18 (1.27–38.08)

0.43 (0.15–2.12)

C-reactive protein, mg/dl, median (IQR)

10 (1–21.3)

12 (2.47–18.55)

3.95 (0.28–13.78)

White blood cell, 103/μL, median (IQR)

13.2 (6.8–18.7)

11.1 (4.75–18.55)

15.15 (11.63–19.2)

Interleukin −8, pg/ml, median (IQR)

85.3 (23.88–335)

193.5 (54.35–965.5)

36.65 (15.95–93.1)

Interleukin-10, pg/ml, median (IQR)

10 (3–45)

17 (5–75.25)

5 (2–16)

Tumor necrosis factor-α, pg/ml, median (IQR)

3.91 (1.68–8.94)

5.1 (2.47–12.8)

2.33 (1.21–4.11)

Day-1

All (n = 161)

MOD (n = 102)

without MOD (n = 59)

Interleukin-6, pg/ml, median (IQR)

150.7 (57.99–1096)

394.6 (92.83–2163.25)

62.8 (38.4–137.85)

Procalcitonin, ng/ml, median (IQR)

3.3 (0.96–19.75)

7.19 (1.83–34.82)

1.61 (0.49–5)

C-reactive protein, mg/dl, median (IQR)

12 (6.79–21.3)

14.75 (7.72–25.53)

9.9 (5.85–17.05)

White blood cell, 103/μL, median (IQR)

11.9 (8.3–16)

11.8 (7.33–15.98)

11.9 (9.15–16.35)

Interleukin −8, pg/ml, median (IQR)

41.1 (13.2–132)

89.55 (24.8–299.8)

14.2 (9.4–44)

Interleukin-10, pg/ml, median (IQR)

4 (2–12.5)

7 (3–24)

2 (2–4)

Tumor necrosis factor-α, pg/ml, median (IQR)

3.34 (1.94–6.04)

4.04 (2.21–8.2)

2.67 (1.6–4.11)

Day-2

All (n = 161)

MOD (n = 96)

without MOD (n = 65)

Interleukin-6, pg/ml, median (IQR)

102.1 (42.37–262.5)

159.6 (88.86–492.98)

47.53 (24.75–88)

Procalcitonin, ng/ml, median (IQR)

2.62 (0.83–14.62)

6.53 (1.54–25.88)

0.95 (0.39–3.93)

C-reactive protein, mg/dl, median (IQR)

15.5 (9–21.5)

18.1 (10.83–24.08)

11.9 (7–17)

White blood cell, 103/μL, median (IQR)

10.7 (8.2–14.2)

11.5 (7.38–14.75)

9.7 (8.3–13)

Interleukin −8, pg/ml, median (IQR)

25.3 (11.8–82.3)

55.75 (20.58–120.5)

11.8 (5.6–24.4)

Interleukin-10, pg/ml, median (IQR)

2 (2–7)

4 (2–9.5)

2 (2–2)

Tumor necrosis factor-α, pg/ml, median (IQR)

2.93 (2.02–4.75)

3.7 (2.35–5.42)

2.27 (1.77–3.17)