Table 1 Baseline ambulance and hospital admission characteristics of Mimic patients enrolled in the RIGHT-2 trial. Data are number (%), median [IQR], or mean (standard deviation)
| Â | All | GTN | Sham | Difference | 2p |
|---|---|---|---|---|---|
Ambulance data (pre-randomisation) | |||||
 Number of patients | 297 | 134 | 163 |  | |
 Age (years) | 67 (18) | 68 (19) | 66 (18) | 1.7 (− 2.4, 5.9) | 0.41 |
  < 60 (%) | 107 (36) | 49 (37) | 58 (36) |  | |
 60–70 (%) | 45 (15) | 17 (13) | 28 (17) | ||
 70–80 (%) | 55 (19) | 22 (16) | 33 (20) | ||
  ≥ 80 (%) | 90 (30) | 46 (34) | 44 (27) | ||
 Sex (female) (%) | 157 (53) | 74 (55) | 83 (51) | 4.3 (−7.1, 15.7) | 0.46 |
 Time from onset to randomisation (minutes) | 75 [47,126] | 72.5 [48,120] | 79 [46,140] | −6.0 (−19.0, 5.0) | 0.27 |
 ECG, AF/flutter (%) | 29 (13) | 11 (11) | 18 (15) | 3.6 (−5.1, 12.3) | 0.42 |
 Systolic blood pressure (mmHg) | 159 (26) | 155 (24) | 162 (27) | −7.0 (−12.9, − 1.1) | 0.021 |
 Diastolic blood pressure (mmHg) | 91 (16) | 89 (16) | 92 (16) | −2.7 (−6.4, 1.0) | 0.15 |
 Heart rate (bpm) | 83 (19) | 82 (16) | 84 (21) | −1.7 (−5.9, 2.6) | 0.44 |
 Glasgow coma scale | 14 (2) | 14 (2) | 14 (2) | −0.3 (−0.7, 0.1) | 0.13 |
 Glasgow coma scale < 14 (%) | 73 (25) | 39 (29) | 34 (21) | −8.2 (−18.2, 1.8) | 0.11 |
 FAST score (/3) | 2 (1) | 2 (1) | 2 (1) | 0.0 (−0.1, 0.2) | 0.61 |
 FAST score = 3 (%) | 144 (49) | 67 (50) | 77 (48) | −2.9 (−14.3, 8.6) | 0.63 |
Hospital admission data (post randomisation) | |||||
 Number of patients with data | 297 | 134 | 163 |  | |
 Ethnic group, non-white (%) | 35 (13) | 15 (12) | 20 (13) | 1.2 (−6.7, 9.0) | 0.77 |
 Ethnicity, White (%) | 242 (87) | 110 (88) | 132 (87) |  | |
 Ethnicity, Black (%) | 14 (5) | 5 (4) | 9 (6) | ||
 Ethnicity, Asian (%) | 18 (6) | 10 (8) | 8 (5) | ||
 Ethnicity, Other (%) | 3 (1) | 0 (0) | 3 (2) | ||
 Pre-morbid mRS [/5] | 1 [0,3] | 1 [0,3] | 0 [0,3] | 0.00 (0.00, 0.00) | 0.21 |
 Pre-morbid mRS > 2 (%) | 79 (28) | 39 (31) | 40 (26) | −4.7 (−15.3, 5.9) | 0.38 |
Medical history (%) | |||||
 Hypertension | 142 (51) | 61 (49) | 81 (53) | 4.1 (−7.8, 15.9) | 0.50 |
 Diabetes mellitus | 59 (21) | 27 (22) | 32 (21) | −0.6 (−10.3, 9.2) | 0.91 |
 Previous stroke | 85 (31) | 37 (30) | 48 (32) | 2.2 (−8.7, 13.1) | 0.70 |
 Ischaemic heart disease | 58 (21) | 29 (24) | 29 (19) | −4.2 (−14.1, 5.6) | 0.39 |
 Smoking, current | 54 (24) | 26 (25) | 28 (23) | −2.2 (−13.4, 8.9) | 0.69 |
 Antiplatelets | 69 (36) | 36 (40) | 33 (33) | −7.0 (−20.7, 6.7) | 0.32 |
 Anticoagulants | 33 (17) | 15 (17) | 18 (18) | 1.0 (−9.7, 11.7) | 0.86 |
 Either | 96 (51) | 47 (52) | 49 (49) | −3.2 (−17.5, 11.0) | 0.66 |
 OCSP syndrome, TACS (%) | 40 (18) | 15 (16) | 25 (19) | 3.6 (−6.4, 13.6) | 0.49 |
 NIHSS (/42) | 4 [2,8] | 4 [1,9] | 4 [2,7] | 0.0 (−1.0, 1.0) | 0.64 |