Characteristics | Â | FFP group | Cryo group | FFP and cryo group | Control group |
---|
 | (n = 51) | (n = 15) | (n = 24) | (n = 33) |
---|
PT | Fibrinogen | PT | Fibrinogen | PT | Fibrinogen | PT | Fibrinogen |
---|
 | n(%) | n(%) | n(%) | n(%) | n(%) | n(%) | n(%) | n(%) |
Stabilized | 4 (8) | 3 (6) | 2 (13) | 0 | 1 (4) | 0 | 2 (6) | 0 |
Persistent | 20 (39) | 27 (53) | 6 (40) | 12 (80) | 11 (46) | 15 (63) | 8 (24) | 20 (61) |
Recurrent | 2 (4) | 1 (2) | 0 | 0 | 4 (17) | 2 (8) | 2 (6) | 0 |
Late | 25 (49) | 20 (39) | 7 (47) | 3 (20) | 8 (33) | 7 (29) | 21 (64) | 13 (39) |
- Coagulopathy patterns were classified as follow:
- (1) stabilized: the values corrected following the first antivenom administration within 48 h and did not recur;
- (2) persistent: the values did not return to normal by the time of discharge;
- (3) recurrent: the values were abnormal within the first 12 h, became normal,and then returned to abnormal;
- (4) late: the values were abnormal since 12 h or more following the first antivenom administration
- Rows of stabilized and recurrent were excluded for analysis due to 50% cells have expected count less than 5
- No statistical significance of persistent and late coagulopathy were found among four groups(P = 0.21 and P = 0.42, respectively)
- FFP fresh-frozen plasma, cryo cryoprecipitate, PT prothrombin time