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Table 2 Coagulopathy patterns of the patients with and without clotting factor replacement treatment

From: Effectiveness of clotting factor replacement therapy after antivenom treatment on coagulopathic envenomation following green pit viper bites: a retrospective observational study

Characteristics

 

FFP group

Cryo group

FFP and cryo group

Control group

 

(n = 51)

(n = 15)

(n = 24)

(n = 33)

PT

Fibrinogen

PT

Fibrinogen

PT

Fibrinogen

PT

Fibrinogen

 

n(%)

n(%)

n(%)

n(%)

n(%)

n(%)

n(%)

n(%)

Stabilized

4 (8)

3 (6)

2 (13)

0

1 (4)

0

2 (6)

0

Persistent

20 (39)

27 (53)

6 (40)

12 (80)

11 (46)

15 (63)

8 (24)

20 (61)

Recurrent

2 (4)

1 (2)

0

0

4 (17)

2 (8)

2 (6)

0

Late

25 (49)

20 (39)

7 (47)

3 (20)

8 (33)

7 (29)

21 (64)

13 (39)

  1. Coagulopathy patterns were classified as follow:
  2. (1) stabilized: the values corrected following the first antivenom administration within 48 h and did not recur;
  3. (2) persistent: the values did not return to normal by the time of discharge;
  4. (3) recurrent: the values were abnormal within the first 12 h, became normal,and then returned to abnormal;
  5. (4) late: the values were abnormal since 12 h or more following the first antivenom administration
  6. Rows of stabilized and recurrent were excluded for analysis due to 50% cells have expected count less than 5
  7. No statistical significance of persistent and late coagulopathy were found among four groups(P = 0.21 and P = 0.42, respectively)
  8. FFP fresh-frozen plasma, cryo cryoprecipitate, PT prothrombin time