Table 2 Comparison of general characteristics, laboratory values, intensive care measures and outcome parameters between survivors and non-survivors in intoxicated patients.

Age (years) – median (IQR)

41 (29-53)

48 (30-60)

0.32

Age category

-

-

0.61

 Age <65 years

92% (3,906)

88% (28)

-

 Age 65-79 years

6% (243)

9% (3)

-

 Age ≥80 years

2% (86)

3% (1)

-

Sex

-

-

0.27

 Female

55% (2,320)

41% (13)

-

 Male

45% (1,910)

59% (19)

-

 Unknown

0% (3)

0% (0)

-

BMI (kg/m²) – median (IQR)

27 (23-31)

24 (21-30)

0.16

BMI categories (WHO)

-

-

0.030*

 BMI <18.5 kg/m²

4% (156)

13% (4)

-

 BMI 18.5-24.9 kg/m²

36% (1,455)

43% (13)

-

 BMI 25-29.9 kg/m²

30% (1,218)

20% (6)

-

 BMI ≥30 kg/m²

31% (1,254)

23% (7)

-

Ethnicity

-

-

0.93

 African American

8% (322)

6% (2)

-

 Asian

1% (45)

0% (0)

-

 Caucasian

83% (3,435)

84% (27)

-

 Hispanic

3% (111)

3% (1)

-

 Native American

1% (53)

3% (1)

-

 Other/Unknown

4% (161)

3% (1)

-

SOFA score (pts.) – median (IQR)

3 (1-5)

8 (5-11)

<0.001*

APACHE-IV (pts.) – median (IQR)

37 (26-53)

90 (64-113)

<0.001*

Laboratory values – median (IQR)

-

-

-

Maximum lactate day 1 (mmol/L)

1.6 (1.0-2.5)

3.1 (1.7-6.4)

<0.001*

First lactate >2mmol/L

34% (309)

71% (15)

<0.001*

Maximum creatinine day 1 (mg/dL)

0.8 (0.7-1.0)

1.3 (1.0-2.3)

<0.001*

Hemoglobin (g/dL)

12.4 (11.3-13.6)

12.6 (10.4-14.8)

0.68

Platelets (G/L)

210 (169-256)

224.5 (173.0-276.0)

0.40

Leucocytes (G/L)

8.6 (6.5-11.6)

13.0 (9.2-18.2)

<0.001*

Toxin/poison/drug

-

-

0.22

 Overdose alcohols⁽¹⁾

12% (521)

0% (0)

-

 Overdose analgesics⁽²⁾

11% (480)

16% (5)

-

 Overdose antidepressants⁽³⁾

7% (301)

6% (2)

-

 Overdose of other toxin/poison/drug

18% (778)

19% (6)

-

 Overdose sedatives⁽⁴⁾

29% (1,249)

25% (8)

-

 Overdose, street drugs⁽⁵⁾

20% (852)

34% (11)

-

 Drug-toxicity⁽⁶⁾

1% (54)

0% (0)

-

Intensive care measures

-

-

-

 Mechanical ventilation

26% (1,097)

66% (21)

<0.001*

 Vasopressor use

4% (184)

41% (13)

<0.001*

 Dialysis (first three days)

3% (35)

6% (1)

0.50

Outcome

-

-

-

 AKI

2% (47)

9% (2)

0.047*

 LOS (hours)

28 (18-46)

76 (35-175)

<0.001*

 LOS >7 days

2% (103)

25% (8)

<0.001*

 ICU mortality

0% (0)

66% (21)

<0.001*

 Hospital mortality

0% (0)

100% (32)

<0.001*