Table 2 Univariate analysis of pre-traumatic and post-traumatic risk factors with the presence of post-traumatic ICH in patients receiving OAT
Variable | No ICH | ICH | p-value |
|---|---|---|---|
Patients, n (%) | 2764 (90.5) | 290 (9.5) | |
Age in years, median (IQR) | 83 (77-87) | 84 (78-88) | 0.030 |
Sex, n (%) | 0.155 | ||
Male | 1268 (45.9) | 146 (50.3) | |
Female | 1496 (54.1) | 144 (49.7) | |
Oral anticoagulant therapy, n (%) | 0.002 | ||
VKA | 1642 (59.4) | 200 (69) | |
DOACs | 1122 (40.6) | 90 (31) | |
Pre-traumatic risk factors, n (%) | |||
Major trauma dynamic | 94 (3.4) | 42 (14.4) | < 0.001 |
Acute intoxication | 59 (2.1) | 6 (2.1) | 1.000 |
Previous neurosurgery | 66 (2.4) | 20 (6.9) | < 0.001 |
Antiplatelet therapy | 125 (4.5) | 23 (7.9) | 0.014 |
Post-traumatic risk factors, n (%) | |||
Post-traumatic TLOC | 112 (4.1) | 60 (20.7) | < 0.001 |
Post-traumatic amnesia | 208 (7.5) | 89 (30.7) | < 0.001 |
Post-traumatic headache | 85 (3.1) | 27 (9.3) | < 0.001 |
GCS < 15 | 277 (10.0) | 88 (30.3) | < 0.001 |
Focal neurological signs | 23 (0.8) | 15 (5.2) | < 0.001 |
Visibile trauma above the clavicles | 1780 (64.4) | 243 (83.8) | < 0.001 |
Post-traumatic vomiting | 53 (1.9) | 31 (10.7) | < 0.001 |
Post-traumatic seizure | 6 (0.2) | 3 (1.0) | 0.046 |