Positive SI (n = 249) | Negative SI (n = 157) | p value | |
---|---|---|---|
Demographics | |||
Age (years) | 70 ± 15 | 68 ± 16 | 0.247 |
Hypertension | 102 (41%) | 64 (41%) | 0.968 |
Chronic cardiac failure | 33 (13%) | 36 (23%) | 0.012 |
Diabetes Mellitus | 68 (27%) | 38 (24%) | 0.488 |
Cancer history | 88 (35%) | 56 (36%) | 0.946 |
COPD | 30 (12%) | 25 (16%) | 0.268 |
Chronic Renal Failure | 32 (13%) | 20 (13%) | 0.974 |
Prehospital initial values | |||
Initial SBP (mmHg) | 91 ± 26 | 115 ± 31 | < 10–3 |
Initial DBP (mmHg) | 53 ± 17 | 69 ± 21 | < 10–3 |
Initial MBP (mmHg) | 65 ± 19 | 83 ± 22 | < 10–3 |
Initial HR (beats.min−1) | 117 ± 28 | 106 ± 27 | 10–4 |
Initial RR (movements.min−1) | 28 [22-36] | 31 [24-40] | 0.135 |
Initial pulse oximetry (%) | 93 [88 – 97] | 92 [84 – 96] | 0.139 |
Initial body core temperature (°C) | 38.5 [37.0 – 39.4] | 38.4 [37.0 – 39.3] | 0.707 |
Initial Glasgow coma scale | 15 [13-15] | 15 [14-15] | 0.168 |
Initial blood lactate (mmol.l−1) | 6.0 ± 3.6 | 6.8 ± 4.0 | 0.212 |
Fluid expansion (ml) | 750 [500 – 1250] | 500 [500 – 1000] | < 10–3 |
Fluid expansion / body weight (ml.kg−1) | 16 ± 11 | 12 ± 7 | 10–4 |
Norepinephrine administration | 75 (30%) | 25 (16%) | 10–3 |
Norepinephrine dose (mg.h−1) | 1.0 [0.6 – 2.0] | 1.0 [0.5 – 2.0] | 0.676 |
Prehospital AB administration | 80 (32%) | 34 (22%) | 0.023 |
Prehospital duration (min) | 70 ± 31 | 56 ± 30 | < 10–3 |
Prehospital final values | |||
Final SBP (mmHg) | 110 ± 25 | 92 ± 25 | < 10–3 |
Final DBP (mmHg) | 63 ± 19 | 54 ± 16 | < 10–3 |
Final MBP (mmHg) | 78 ± 20 | 67 ± 18 | < 10–3 |
Final HR (beats.min−1) | 104 ± 25 | 110 ± 26 | 0.010 |
Final RR (movements.min−1) | 24 [19-32] | 28 [21-35] | 0.022 |
Final pulse oximetry (%) | 97 [95 – 99] | 97 [93 – 99] | 0.198 |
Final body core temperature (°C) | 38.2 [36.9 – 39.0] | 38.1 [37.0 – 39.0] | 0.900 |
Final Glasgow coma scale | 15 [14-15] | 15 [14-15] | 0.149 |
Final blood lactate (mmol.l−1) | 4.4 ± 3.6 | 4.5 ± 3.7 | 0.823 |
Delta blood lactate (mmol.l−1) | 1.1 ± 2.8 | 1.3 ± 2.7 | 0.659 |
Positive delta blood lactate | 81 (32%) | 34 (22%) | 0.994 |
Negative delta blood lactate | 37 (15%) | 17 (11%) | 0.708 |
Hospital parameters | |||
SOFA score | 7 [4-10] | 8 [2-10] | 0.501 |
SAPS2 score | 56 ± 21 | 61 ± 23 | 0.115 |
In-ICU length of stay (days) | 5 [3-8] | 4 [2-9] | 0.326 |
In-hospital length of stay (days) | 12 [7-20] | 11 [6-20] | 0.258 |