Table 5 Estimation sample baseline (\({S}_{0})\) and final (\({S}_{T}\)) pain scores by treatment group
Methoxyflurane | Entonox® | Paracetamol IV | Morphine IV | |||||
|---|---|---|---|---|---|---|---|---|
Pain score | \({S}_{0}\) (n = 429) | \({S}_{T}\) (n = 429) | \({S}_{0}\) (n = 753) | \({S}_{T}\) (n = 753) | \({S}_{0}\) (n = 278) | \({S}_{T}\) (n = 278) | \({S}_{0}\) (n = 802) | \({S}_{T}\) (n = 802) |
Mean | 8.7 | 4.5 | 7.8 | 5.6 | 7.2 | 4.8 | 8.3 | 5.0 |
Standard deviation | 1.6 | 2.8 | 1.8 | 2.5 | 1.8 | 2.3 | 1.6 | 2.6 |
Severe | ||||||||
10 | 46.4% | 5.1% | 23.2% | 8.1% | 16.9% | 3.2% | 34.4% | 5.2% |
9 | 11.0% | 4.0% | 13.7% | 4.8% | 8.3% | 1.8% | 14.7% | 4.6% |
8 | 21.5% | 9.3% | 24.8% | 13.0% | 23.0% | 8.6% | 24.1% | 10.7% |
7 | 10.0% | 7.0% | 12.5% | 12.6% | 15.8% | 10.1% | 11.2% | 10.6% |
Moderate | ||||||||
6 | 6.1% | 9.8% | 11.4% | 14.2% | 15.1% | 16.9% | 7.6% | 11.5% |
5 | 4.0% | 17.7% | 8.9% | 17.0% | 16.6% | 20.9% | 6.2% | 17.7% |
4 | 0.7% | 11.2% | 5.4% | 11.8% | 4.3% | 14.0% | 1.8% | 14.2% |
Mild | ||||||||
3 | 0.5% | 8.9% | - | 6.4% | - | 8.6% | - | 7.0% |
2 | - | 10.7% | - | 6.6% | - | 7.6% | - | 8.9% |
1 | - | 4.9% | - | 1.5% | - | 3.2% | - | 2.4% |
None | ||||||||
0 | - | 11.4% | - | 4.0% | - | 5.0% | - | 7.2% |
Duration in minutes | ||||||||
First to baseline | 8.4 (10.5; 0.0–85.5) | 9.8 (10.3; 0.0–79.0) | 17.1 (10.6; 0.4–52.5) | 14.9 (10.6; 0.2–61.9) | ||||
Baseline to final | 26.1 (11.4; 1.0–47.5) | 24.7 (16.1; 1.0–87.3) | 26.7 (13.8; 5.0–68.5) | 27.3 (16.7; 1.0–80.5) | ||||