Table 1 Comparisons of patient characteristics before and during the Coivd-19 pandemic

Demographics

 Age, year

885

67.0 ± 13.9^*

66.9 ± 12.1

67.5 ± 12.8

0.604

372

61.2 ± 15.1

60.8 ± 15.2

62.9 ± 14.4

0.303

 Male, %

886

521(59.0)^*

427(58.9)

96(59.6)

0.873

373

274(73.5)

224(73.2)

50(74.6)

0.811

 Height, cm

856

163.0 ± 9.4^*

162.8 ± 9.6

164.1 ± 8.5

0.106

363

165.2 ± 8.9

164.8 ± 8.9

166.5 ± 8.7

0.166

 Weight, kg

758

63.2 ± 29.0^*

63.0 ± 31.3

64.1 ± 12.8

0.499

309

67.8 ± 15.6

67.6 ± 15.5

69.3 ± 16.1

0.478

 BMI, kg/m2

750

23.8 ± 12.4

23.8 ± 13.5

23.7 ± 3.8

0.925

305

24.8 ± 4.7

24.7 ± 4.7

25.2 ± 4.8

0.524

Comorbidities

 DM, N(%)

881

411(46.7)^*

320(44.4)

91(56.5)

0.005

363

112(30.9)

90(30.4)

22(32.8)

0.697

 HT, N(%)

881

460(52.2)^*

381(52.9)

79(49.1)

0.377

363

141(38.8)

108(36.5)

33(49.3_

0.053

 CVD, N(%)

881

280(31.8)^*

220(30.6)

60(37.3)

0.098

363

71(19.6)

54(18.2)

17(25.4)

0.184

 CKD, N(%)

881

138(15.7)

105(14.6)

33(20.5)

0.062

363

43(11.8)

30(10.1)

13(19.4)

0.034

 Liver, N(%)

881

100(11.4)

76(10.6)

24(14.9)

0.116

363

43(11.8)

35(11.8)

8(11.9)

0.979

 Lung, N(%)

881

81(9.2)

67(9.3)

14(8.7)

0.807

363

22(6.1)

19(6.4)

3(4.5)

0.548

 Cancer, N(%)

884

192(21.7)^*

140(19.4)

52(32.3)

< 0.001

373

50(13.4)

37(12.1)

13(19.4)

0.112

Disease severity upon hospital arrival

 Organ failure

  Circulatory

871

436(50.1)

361(50.8)

75(46.6)

0.329

318

198(62.3)^ǂ

157(60.6)

41(69.5)

0.204

  Respiratory

872

295(33.8)

233(32.8)

62(38.5)

0.165

318

189(59.4)^ǂ

155(59.8)

34(57.6)

0.754

  Kidney failure

886

309(34.9)^*

262(36.1)

47(29.2)

0.094

373

62(16.6)

48(15.7)

14(20.9)

0.300

Disease severity at CRRT

 Hours from ICU to RRT

882

0(0, 1)

0(0, 1)

1(0, 2)

0.295

373

1(0, 4)

1(0, 4.5)

1(0, 3)

0.141

 Organ failure

  Circulatory

883

576(65.2)

474(65.7)

102(63.4)

0.580

372

270(72.6)^ǂ

220(72.1)

50(74.6)

0.678

  Respiratory

883

453(51.3)

365(50.6)

88(54.7)

0.346

372

300(80.6)^ǂ

249(81.6)

51(76.1)

0.300

  Number

883

2.2 ± 0.8

2.2 ± 0.8

2.2 ± 0.8

0.813

372

2.5 ± 0.7^ǂ

2.5 ± 0.7

2.5 ± 0.7

0.748

Lab values at CRRT initiation

 WBC, 10E3/uL

883

14.3 ± 11.7

14.4 ± 11.8

13.7 ± 11.5

0.463

370

11.5 ± 8.4

11.5 ± 8.3

11.3 ± 8.9

0.845

 Hb, g/dL

882

10.2 ± 3.8

10.3 ± 3.9

10.3 ± 2.5

0.137

370

10.2 ± 4.3

10.2 ± 4.6

10.1 ± 1.8

0.911

 PLT, 10E3/uL

883

155.3 ± 110.8

156.4 ± 110.3

150.6 ± 113.0

0.547

371

124.3 ± 79.3^ǂ

127.2 ± 82.7

112.2 ± 59.8

0.137

 TP, g/dL

879

5.9 ± 5.4

5.9 ± 5.9

5.5 ± 1.2

0.280

372

5.0 ± 1.0^ǂ

5.0 ± 0.9

4.9 ± 0.9

0.494

 Albumin, g/dL

880

3.0 ± 0.7

3.0 ± 0.7

3.0 ± 0.7

0.886

372

2.9 ± 0.6

2.9 ± 0.5

2.9 ± 0.8

0.575

 BUN, mg/dL

882

62.7 ± 38.7^*

61.5 ± 38.9

67.9 ± 37.3

0.055

372

48.7 ± 33.1

47.7 ± 32.6

53.1 ± 34.9

0.230

 Cr, mg/dL

882

3.8 ± 4.1^*

3.7 ± 4.3

4.1 ± 3.0

0.259

372

2.9 ± 2.0

2.8 ± 2.1

3.1 ± 1.7

0.262

 Na, mmol/L

883

135.4 ± 7.8^*

135.1 ± 7.8

136.5 ± 8.1

0.049

372

140.3 ± 6.3

140.6 ± 6.1

139.1 ± 6.7

0.072

 K, mmol/L

883

4.7 ± 4.4

4.8 ± 4.8

4.6 ± 1.0

0.719

372

4.5 ± 1.0

4.5 ± 1.0

4.6 ± 1.0

0.581

 tCO2, mmol/L

754

15.4 ± 7.4^*

15.4 ± 7.6

15.5 ± 5.4

0.929

224

18.9 ± 11.9

19.1 ± 12.0

16.4 ± 6.7

0.530

 PT, INR

752

1.8 ± 1.9

2.1 ± 3.6

1.8 ± 1.3

0.058

323

1.7 ± 1.1

1.7 ± 1.2

1.8 ± 0.6

0.728