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Table 3 Diagnostic test characteristics for applying Age Adjusted Threshold after exclusions

From: The application of an age adjusted D-dimer threshold to rule out suspected venous thromboembolism (VTE) in an emergency department setting: a retrospective diagnostic cohort study

Statistic

95% Confidence Interval (all VTE)

95% Confidence Interval (DVT only)

95% Confidence Interval (PE only)

Sensitivity

98.67% (96.17–99.73)

99.28% (96.06–99.98)

97.70% (91.94–99.72)

Specificity

31.09% (28.24- 34.05)

33.43 (29.95–37.05)

25.73% (20.94–31.01)

Positive likelihood ratio

1.43 (1.37–1.50)

1.49 (1.41–1.57)

1.32 (1.22–1.42)

Negative likelihood ratio

0.04 (0.01–0.13)

0.02 (0.00–0.15)

0.09 (0.02–0.36)

Positive predictive value

24.4% (23.46- 25.09)

22.77% (21.83–23.74)

27.16% (25.73–28.63)

Negative predictive value

99.00% (97.13–99.69)

99.58% (21.83–23.74)

97.53% (90.83–99.37)

Disease prevalence

18.28 16.17–20.55

16.51 (14.06–19.19)

22.08 (18.08–26.51)