Variable | Patients with infection | Patients without infection | |||
---|---|---|---|---|---|
Number (%) n = 553 | Median (IQR) | Number (%) n = 318 | Median (IQR) | P-value* | |
Age (years) | 78 (71–85) | 74 (59–83) | < 0.001 | ||
Gender | 0.054 | ||||
-male | 331 (59.9) | 169 (53.1) | |||
Ambulance priority | < 0.001 | ||||
(n**) | 547 | 313 | |||
1 | 100 (18.3) | 19 (6.1) | |||
2 | 386 (70.6) | 246 (78.6) | |||
3 | 61 (11.2) | 48 (15.3) | |||
Keywords related to medical history | |||||
1. Fever or suspected fever | < 0.001 | ||||
(n**) | 552 | 316 | |||
yes | 404 (73.2) | 31 (9.8) | |||
no | 134 (24.3) | 279 (88.3) | |||
inability to answer | 14 (2.5) | 6 (1.9) | |||
2. Pain | 0.017 | ||||
(n**) | 551 | 315 | |||
yes | 256 (46.5) | 145 (46.0) | |||
no | 274 (49.7) | 168 (53.3) | |||
inability to answer | 21 (3.8) | 2 (0.6) | |||
3. Acute altered mental status | < 0.001 | ||||
(n**) | 552 | 316 | |||
yes | 328 (59.4) | 70 (22.2) | |||
no | 208 (37.7) | 242 (76.6) | |||
inability to answer | 16 (2.9) | 4 (1.2) | |||
4. Weakness of the legs*** | < 0.001 | ||||
(n**) | 552 | 316 | |||
yes | 420 (76.1) | 105 (33.2) | |||
no | 109 (19.7) | 205 (64.9) | |||
inability to answer | 23 (4.2) | 6 (1.9) | |||
5. Breathing difficulties | < 0.001 | ||||
(n**) | 550 | 315 | |||
yes | 280 (50.9) | 70 (22.2) | |||
no | 251 (45.6) | 240 (76.2) | |||
inability to answer | 19 (3.4) | 5 (1.6) | |||
6. Loss of energy | < 0.001 | ||||
(n**) | 552 | 315 | |||
yes | 491 (88.9) | 162 (51.4) | |||
no | 50 (9.1) | 148 (47.0) | |||
inability to answer | 11 (2.0) | 5 (1.6) | |||
7. Gastrointestinal symptoms:vomiting/diarrhoea | < 0.001 | ||||
(n**) | 551 | 316 | |||
yes | 188 (34.1) | 67 (21.2) | |||
no | 337 (61.2) | 247 (78.2) | |||
inability to answer | 26 (4.7) | 2 (0.6) | |||
8. Risk factors for sepsis**** | < 0.001 | ||||
(n**) | 550 | 315 | |||
yes | 229 (41.6) | 33 (10.5) | |||
no | 294 (53.4) | 275 (87.3) | |||
inability to answer | 27 (4.9) | 7 (2.2) | |||
Vital parameters | |||||
1. Respiratory rate (min−1) | 21 (18–28) | 16 (15–19) | < 0.001 | ||
2. Oxygen saturation (%) | 94 (91–97) | 97 (95–99) | < 0.001 | ||
3. Heart rate (min−1) | 94 (80–109) | 80 (70–95) | < 0.001 | ||
4. Systolic BP (mmHg) | 135 (120–150) | 140 (124–160) | < 0.001 | ||
5. GCS (score) | 15 (15–15) | 15 (15–15) | < 0.001α | ||
6. Temperature (°C) | 38.3 (37.5–39.1) | 36.8 (36.5–37.1) | < 0.001 | ||
Blood tests | |||||
1. P-Glucose (mmol/L) | 7.8 (6.8–9.7) | 7.1 (6.1–8.6) | < 0.001 | ||
2. P-Lactate (mmol/L) | 1.7 (1.3–2.6) | 1.6 (1.2–2.4) | 0.103 | ||
3. P-suPAR (ng/mL) | 4.8 (3.5–6.7) | 3.5 (2.5–4.7) | < 0.001 | ||
4. P-HBP (ng/mL) | 12.9 (5.9–28.4) | 5.9 (5.9–9.7) | < 0.001 | ||
Comorbidity | |||||
Charlson comorbidity score | 2 (1–4) | 1 (0–2) | < 0.001 | ||
Admitted to in-hospital care | 455 (82.3) | 179 (56.3) | < 0.001 | ||
Sepsis within 36 h | 230/551 (41.7) | 12/317 (3.8) | < 0.001 | ||
In-hospital mortality | 33 (6.0) | 8 (2.5) | 0.021 |