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Table 2 Cases of splenic rupture associated with previously undiagnosed infiltrative or inflammatory pathology

From: 613 cases of splenic rupture without risk factors or previously diagnosed disease: a systematic review

Disease Cases References
Infectious   
  Malaria 65 [4960]
  Mononucleosis 42 [6190]
  CMV 6 [9195]
  Typhoid fever 4 [96, 97]
  Endocarditis with splenic embolism 3 [98100]
  Pneumonia 3 [101103]
  HIV 3 [104106]
  Q fever 2 [107, 108]
  Salmonella sp. 2 [109, 110]
  Splenic tuberculosis 2 [111, 112]
  Viral Hepatitis 2 [113, 114]
  EBV 1 [115]
  Babesiosis 1 [116]
  Brucellosis 1 [117]
  Bartonella 1 [118]
  Dengue fever 1 [119]
  Enterobacter cloacae 1 [120]
  Murine typhus 1 [121]
  Rickettsia sp. 1 [122]
  Varicella 1 [123]
Haematologic
  Non-Hodgkin’s Lymphoma 25 [124145]
  Hodgkin’s Lymphoma 5 [146150]
  Undifferentiated Lymphoma 3 [151153]
  Acute Lymphoblastic Leukemia 18 [154165]
  Chronic Myelogenous Leukemia 7 [166172]
  Acute Myelogenous Leukemia 6 [64, 173177]
  Hairy Cell Leukemia 5 [178182]
  Acute T-cell Leukemia 1 [183]
  Undfifferentiated Leukemia 1 [184]
  Histiocytosis 6 [185190]
  Multiple Myeloma 2 [63, 191]
  Idiopathic Thrombocytic Purpura 1 [192]
  Myelofibrosis 1 [193]
  Polycythemia Vera 1 [194]
  Sickle Cell Disease 1 [195]
  Essential Thrombocythemia 1 [196]
Rheumatologic   
  Wegener’s Granulomatosis 3 [197199]
  Polyarteritis Nodosa 3 [200, 201]
  Systemic Lupus Erythematosis 3 [202204]
  Rheumatoid Arthritis 1 [205]
Other   
  Amyloidosis 24 [65, 206216]
  Peliosis 8 [217224]
  Pancreatitis 5 [151, 225228]
  Gaucher’s Disease 1 [80]
  Wilson’s Disease 1 [229]
Total 276