Objective
To study the effect of the Xuebijing oral solution on survival of rabbits with acute paraquat poisoning.
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Effect of the Xuebijing oral solution on survival of rabbits with acute paraquat poisoning
BMC Emergency Medicine volume 12, Article number: A6 (2012)
Methods
30 New Zealand white rabbits were randomly divided into saline control group(group A) and two treatment groups of 3ml/kg(group B) and 10ml/kg(group C) of Xuebijing oral solution.All the rabbits were treated with PQ at 35mg/kg through intraperitoneal injection, which would build the model of acute poisoning. Group B and C were treated by gavage with 3ml/kg and 10ml/kg of Xuebijing oral solution respectively, once a day to maintain. Group A were treated with saline instead.
Results
The analysis of survival curve showed that the survival rate was not significantly different between group A and B, but group C was significantly higher than group A and B(P<0.05).
Conclusion
Large doses of Xuebijing oral solution may improve the survival rate of acute paraquat poisoning.
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Open Access This article is published under license to BioMed Central Ltd. This is an Open Access article is distributed under the terms of the Creative Commons Attribution License ( https://creativecommons.org/licenses/by/2.0 ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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Zu-jun, S., Gao-fei, C., Guo-kun, A. et al. Effect of the Xuebijing oral solution on survival of rabbits with acute paraquat poisoning. BMC Emerg Med 12 (Suppl 1), A6 (2012). https://doi.org/10.1186/1471-227X-12-S1-A6
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DOI: https://doi.org/10.1186/1471-227X-12-S1-A6
Keywords
- Public Health
- Treatment Group
- Survival Rate
- Emergency Medicine
- Survival Curve