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  • Meeting abstract
  • Open Access

Effect of the Xuebijing oral solution on survival of rabbits with acute paraquat poisoning

BMC Emergency Medicine201212 (Suppl 1) :A6

https://doi.org/10.1186/1471-227X-12-S1-A6

  • Published:

Keywords

  • Public Health
  • Treatment Group
  • Survival Rate
  • Emergency Medicine
  • Survival Curve

Objective

To study the effect of the Xuebijing oral solution on survival of rabbits with acute paraquat poisoning.

Methods

30 New Zealand white rabbits were randomly divided into saline control group(group A) and two treatment groups of 3ml/kg(group B) and 10ml/kg(group C) of Xuebijing oral solution.All the rabbits were treated with PQ at 35mg/kg through intraperitoneal injection, which would build the model of acute poisoning. Group B and C were treated by gavage with 3ml/kg and 10ml/kg of Xuebijing oral solution respectively, once a day to maintain. Group A were treated with saline instead.

Results

The analysis of survival curve showed that the survival rate was not significantly different between group A and B, but group C was significantly higher than group A and B(P<0.05).

Conclusion

Large doses of Xuebijing oral solution may improve the survival rate of acute paraquat poisoning.

Authors’ Affiliations

(1)
Department of Emergency The 309th Hospital of Chinese People’s Liberation Army, 17 Heishanhu Road, Haidian District, Beijing, 100091, People’s Republic of China
(2)
The Fourth Military Medical University, No.127 Changle Xilu Road Xi'an, 710032, People’s Republic of China
(3)
Department of Rodiology The 309th Hospital of Chinese People’s Liberation Army, 17 Heishanhu Road, Haidian District, Beijing, 100091, People’s Republic of China

Copyright

© Zu-jun et al; licensee BioMed Central Ltd. 2012

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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