- Meeting abstract
- Open Access
Clinical usefulness of T-SPOT.TB in the diagnosis tuberculosis in emergency patients
- HU Xiao-min1,
- LIU Jian1,
- LEI Long1 and
- YIN Wen1Email author
https://doi.org/10.1186/1471-227X-12-S1-A7
© Xiao-min et al; licensee BioMed Central Ltd. 2012
- Published: 18 December 2012
Keywords
- Polymerase Chain Reaction
- Tuberculosis
- Mononuclear Cell
- Peripheral Blood Mononuclear Cell
- Clinical Usefulness
Objective
To evaluate the diagnostic value of an interferon-gamma release assay T-SPOT.TB in tuberculosis of emergency patients.
Methods
The emergency patients with suspected tuberculosis received T-SPOT.TB assay in the peripheral blood mononuclear cells(PBMCs).
Results
T-SPOT.TB assay, PPD, anti-TB antibody test, M tuberculosis polymerase chain reaction, acid-fast bacilli stain and cultures for M tuberculosis were positive in 96.8%(31/32), 43.7%(14/32), 21.8%(7/32), 15.6%(5/32), 13.0%(3/23) and 4.3%(1/23), respectively, of patients with active tuberculosis. The sensitivity and specificity of the T-SPOT.TB were 96.8% and 98.3%.
Conclusions
T-SPOT.TB assay is a rapid and high-sensitive tests for diagnosing tuberculosis in emergency patients.
Authors’ Affiliations
Copyright
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
