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Table 3 Controlled nodes and controlling nodes for the CPF (fed) group

From: Metabolic networks in a porcine model of trauma and hemorrhagic shock demonstrate different control mechanism with carbohydrate pre-feed

Controlled node

Controlling node (sign)

Adenosine

PAA (āˆ’); AHB (+); Lactate (āˆ’)

Cytidine

PAA (āˆ’); AHB (+); Formate (āˆ’)

Glycerol

Citrate (āˆ’); Acetoacetate (+); Lactate (āˆ’)

Hypoxanthine

Alanine (āˆ’); Glutamate (+)

Lactate

Alanine (āˆ’); Glutamate (+); DMA (+)

Uridine

PAA (āˆ’); Phenylacetate (+)

  1. The sign indicates the direction of the interaction relative to the controlled node. (+) indicates that an increase in the level of the controlling node will lead to an increase in the controlled node; (āˆ’) indicates that an increase in the level of the controlling node will lead to a decrease in the controlled node
  2. PAA phenylalanine, AHB 2-hydroxybutyrate, DMA dimethylamine