Table 4 Performance of C-reactive protein values, MAS and their combinations in the diagnosis of acute appendicitis
Sensitivity (95% CI) | Specificity (95% CI) | PPV (95% CI) | NPV (95% CI) | LR+ (95% CI) | LR- (95% CI) | |
|---|---|---|---|---|---|---|
MAS > 4 alone | 56 (50–61) | 64 (57–71) | 74 (68–79) | 44 (38–51) | 1.55 (1.16–2.1) | 0.68 (0.54–0.87) |
Elevated admission CRP | 73 (68–78) | 53 (45–60) | 74 (69–78) | 52 (44–59) | 1.55 (1.23–1.95) | 0.50 (0.36–0.71) |
Positive delta CRP | 84 (79–87) | 19 (13–26) | 66 (61–71) | 38 (27–50) | 1.03 (0.90–1.17) | 0.84 (0.50–1.61) |
MAS combined with admission CRP | 41 (36–47) | 80 (73–85) | 79 (72–85) | 42 (37–48) | 2.05 (1.33–3.13) | 0.73 (0.62–0.87) |
MAS combined with delta CRP | 42 (37–48) | 76 (69–82) | 76 (69–82) | 42 (36–47) | 1.75 (1.19–2.66) | 0.76 (0.63–0.91) |