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Table 3 Clinical course and outcome of patients with severe TBI receiving low- or high-volume prehospital fluid replacement therapy after trauma

From: Enhanced prehospital volume therapy does not lead to improved outcomes in severely injured patients with severe traumatic brain injury

Patient characteristics

Values for low- and high-volume groups

Low-volume

(0-1000 ml)

High-volume

(≥1501 ml)

Group mean

(all patients)

p-values

Emergency surgery (%)

6.2

6.8

6.6

1

Days in the intensive care unit (MV, SD)

16.2 ± 16.3

14.5 ± 14.4

15.3 ± 15.4

0.4

Days intubated (MV, SD)

11.9 ± 14.4

11.4 ± 12.3

11.6 ± 13.4

0.97

Organ failure (%)

77.1

83.8

80.5

0.21

Multi-organ failure (%)

61.1

67.7

64.4

0.3

Sepsis (%)

13.5

9.3

11.5

0.33

RISC prognosis (MV, SD)

44.6 ± 30

49.8 ± 29.6

47.2 ± 30.3

0.1

Died in hospital (%)

45.6

45.6

45.6

1

Died within the first 24 h (%)

23.1

24.9

24

0.8

Days of hospitalization (MV, SD)

25.1 ± 33.9

23.5 ± 31.1

24.3 ± 32.5

0.46

Glasgow Outcome Scale

 dead (%)

46.1

47.0

46.5

0.7

 apallic (%)

9

7.9

8.5

0.7

 strongly handicapped (%)

17.4

22.6

19.9

0.7

 mildly handicapped (%)

17.4

12.8

15.1

0.7

 recovered well (%)

10.2

9.8

10

0.7

  1. Values are the mean, standard deviation (SD) or % of the group. RISC Revised Injury Severity Classification, TBI Traumatic Brain Injury