| | per SD from mean of log-transformed penKid | ***penKid > 100 pmol/L |
|---|
*No eGFR adjustment | **eGFR adjusted | No eGFR adjustment | eGFR adjusted |
|---|
arSOFA = 0 |
OR | 2.6 | 1.7 | 5.5 | 3.2 |
(95% CI) | (1.4–4.9) | (0.9–3.2) | (2.21–13.92) | (1.1–9.1) |
p-value | =0.002 | =0.094 | < 0.0001 | =0.033 |
brSOFA ≤ 1 |
OR | 3.6 | 2.1 | 10.1 | 3.7 |
(95% CI) | (1.9–6.8) | (1.0–4.4) | (3.2–31.7) | (1.0–13.1) |
p-value | < 0.0001 | =0.042 | < 0.0001 | =0.045 |
- *Obtained from logistic regression model adjusted for sex, age. **Logistic regression model adjusted for sex, age and eGFR, by Modification of Diet in Renal Disease (MDRD) Study [18] formula. ***Cutoff of 100 pmol/L has been suggested previously as significantly increased risk for renal deterioration. aPresenting with an rSOFA score = 0 (intact renal function) and being up-classified to a higher rSOFA category within 48 h. Observed 29 up-classifications among 359 patients. bPresenting with an rSOFA score ≤ 1 (intact and moderately impaired) renal function and being up-classified to an rSOFA category of 2 or higher within 48 h. Observed 17 up-classification among 447 patients
