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Table 1 Patient and study characteristics for Cohort 1

From: Oxygen therapy in patients with ST elevation myocardial infarction based on the culprit vessel: results from the randomized controlled SOCCER trial

Characteristics

O2 group (n = 46)

Air group (n = 49)

P-value

Demographics

 Male sex [n (%)]

29 (63.0)

34 (69.4)

NS

 Age (year) [mean (SD)]

63.7 (13.1)

65.5 (11.5)

NS

 BMI [mean (SD)]

26.1 (3.4)

27.0 (4.2)

NS

 Smokera [n (%)]

31 (67.4)

33 (67.3)

NS

Medical history [n (%)]

 Diabetes

3 (6.5)

9 (18.4)

NS

 Hypertension

11 (24.0)

21 (43.0)

NS

 Previous stroke/TIA

0 (0)

3 (6.1)

NS

Previous medication [n (%)]

 ACEi

8 (17.4)

5 (10.2)

NS

 Anticoagulant

1 (2.2)

0 (0)

NS

 ARBs

2 (4.3)

2 (4.1)

NS

 Aspirin

6 (13.0)

3 (6.1)

NS

 β-blocker

0 (0)

7 (14.3)

NS

 CCB

1 (2.2)

7 (14.3)

NS

 Diuretics

1 (2.2)

7 (14.3)

NS

 Statins

2 (4.3)

5 (10.2)

NS

Process times (min) [mean (SD)]

 Symptom to ambulance arrival

110.9 (112.6)

98.2 (87.8)

NS

 Symptom to PCI

175.9 (121.6)

161.3 (93.1)

NS

 Patient’s home to PCI

39.4 (11.2)

37.4 (10.4)

NS

Duration of study intervention (O2 or room air)

 Time (min) [mean (SD)]

85.6 (27.7)

85.4 (25.8)

NS

 Intervention not for entire duration [n (%)]

3 (6.5)b

5 (10.2)c

NS

Vital parameters at inclusion

 Heart rate (BPM) [mean (SD)]

84.2 (17.3)

82.7 (18.2)

NS

 Blood pressure (mmHg) [mean systolic pressure (SD)]

154.0 (29.6)

153.7 (29.1)

NS

 Blood pressure (mmHg) [mean diastolic pressure (SD)]

94.7 (17.0)

91.4 (20.0)

NS

 Blood oxygen saturation [mean (SD)]

98.0 (1.7)

97.7 (1.6)

NS

Vital parameters at arrival to the PCI laboratory

 Heart rate (BPM) [mean (SD)]

74 (13.1)

75 (18.9)

NS

 Blood pressure (mmHg) [mean systolic pressure (SD)]

142.3 (22.2)

140.4 (23.8)

NS

 Blood pressure (mmHg) [mean diastolic pressure (SD)]

85.3 (15.3)

84.8 (14.6)

NS

Blood oxygen saturation [mean (SD)]

99.2 (1.1)

97.0 (1.9)

< 0.001

Killip class [n (%)]

 Class I

45 (97.8)

48 (98.0)

NS

 Class II

1 (2.2)

1 (2.0)

NS

  1. ACEi Angiotensin Converting Enzyme Inhibitor, ARBs Angiotensin II Receptor Blockers, BMI Body Mass Index, BPM Beats Per Minute, CCB Calcium Channel Blocker, NS Not Significant, PCI Percutaneous Coronary Intervention, TIA Transitory Ischemic Attack
  2. aBoth current and past smoker
  3. bThe group allocation was unclear to the PCI personnel in two cases and in one case, the O2 therapy was terminated because the patient had chronic obstructive pulmonary disease
  4. cAll patients received supplemental O2 due to fall in O2 saturation < 94%
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BMC Emergency Medicine

ISSN: 1471-227X

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