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Table 1 Patient and study characteristics for Cohort 1

From: Oxygen therapy in patients with ST elevation myocardial infarction based on the culprit vessel: results from the randomized controlled SOCCER trial

CharacteristicsO2 group (n = 46)Air group (n = 49)P-value
Demographics
 Male sex [n (%)]29 (63.0)34 (69.4)NS
 Age (year) [mean (SD)]63.7 (13.1)65.5 (11.5)NS
 BMI [mean (SD)]26.1 (3.4)27.0 (4.2)NS
 Smokera [n (%)]31 (67.4)33 (67.3)NS
Medical history [n (%)]
 Diabetes3 (6.5)9 (18.4)NS
 Hypertension11 (24.0)21 (43.0)NS
 Previous stroke/TIA0 (0)3 (6.1)NS
Previous medication [n (%)]
 ACEi8 (17.4)5 (10.2)NS
 Anticoagulant1 (2.2)0 (0)NS
 ARBs2 (4.3)2 (4.1)NS
 Aspirin6 (13.0)3 (6.1)NS
 β-blocker0 (0)7 (14.3)NS
 CCB1 (2.2)7 (14.3)NS
 Diuretics1 (2.2)7 (14.3)NS
 Statins2 (4.3)5 (10.2)NS
Process times (min) [mean (SD)]
 Symptom to ambulance arrival110.9 (112.6)98.2 (87.8)NS
 Symptom to PCI175.9 (121.6)161.3 (93.1)NS
 Patient’s home to PCI39.4 (11.2)37.4 (10.4)NS
Duration of study intervention (O2 or room air)
 Time (min) [mean (SD)]85.6 (27.7)85.4 (25.8)NS
 Intervention not for entire duration [n (%)]3 (6.5)b5 (10.2)cNS
Vital parameters at inclusion
 Heart rate (BPM) [mean (SD)]84.2 (17.3)82.7 (18.2)NS
 Blood pressure (mmHg) [mean systolic pressure (SD)]154.0 (29.6)153.7 (29.1)NS
 Blood pressure (mmHg) [mean diastolic pressure (SD)]94.7 (17.0)91.4 (20.0)NS
 Blood oxygen saturation [mean (SD)]98.0 (1.7)97.7 (1.6)NS
Vital parameters at arrival to the PCI laboratory
 Heart rate (BPM) [mean (SD)]74 (13.1)75 (18.9)NS
 Blood pressure (mmHg) [mean systolic pressure (SD)]142.3 (22.2)140.4 (23.8)NS
 Blood pressure (mmHg) [mean diastolic pressure (SD)]85.3 (15.3)84.8 (14.6)NS
Blood oxygen saturation [mean (SD)]99.2 (1.1)97.0 (1.9)< 0.001
Killip class [n (%)]
 Class I45 (97.8)48 (98.0)NS
 Class II1 (2.2)1 (2.0)NS
  1. ACEi Angiotensin Converting Enzyme Inhibitor, ARBs Angiotensin II Receptor Blockers, BMI Body Mass Index, BPM Beats Per Minute, CCB Calcium Channel Blocker, NS Not Significant, PCI Percutaneous Coronary Intervention, TIA Transitory Ischemic Attack
  2. aBoth current and past smoker
  3. bThe group allocation was unclear to the PCI personnel in two cases and in one case, the O2 therapy was terminated because the patient had chronic obstructive pulmonary disease
  4. cAll patients received supplemental O2 due to fall in O2 saturation < 94%