Table 3 Antibiotic use and microbiological outcomes in patients with an ED diagnosis of UTI syndromes
UTI | Pyelonephritis | Urosepsis | ||
|---|---|---|---|---|
Admitted | Not admitted | |||
Total | 83 (100.0) | 108 (100.0) | 56 (100.0) | 42 (100.0) |
Empirical antibiotica | ||||
Piperacillin / tazobactam | 25 (33.3) | 1 (1.0) | 42 (72.4) | 30 (62.5) |
Nitrofurantoin | 15 (20.0) | 35 (33.7) | 0 (0.0) | 1 (2.1) |
Ciprofloxacin | 10 (13.3) | 18 (17.3) | 11 (19.0) | 4 (8.3) |
Trimethoprim | 6 (8.0) | 19 (18.3) | 0 (0.0) | 0 (0.0) |
Amoxicillin / clavulanic acid | 7 (9.3) | 9 (8.7) | 3 (5.2) | 3 (6.2) |
Other | 12 (16.0) | 22 (21.2) | 2 (3.4) | 10 (20.8) |
Urinary culture resultsa | ||||
Positive (> 105 cfu/mL) | 22 (26.5) | 43 (39.8) | 20 (35.7) | 10 (23.8) |
E. coli | 18 (21.7) | 34 (31.5) | 14 (25.0) | 9 (21.4) |
K. pneumoniae | 0 (0.0) | 1 (0.9) | 2 (3.6) | 0 (0.0) |
P. mirabilis | 1 (1.2) | 2 (1.9) | 1 (1.8) | 0 (0.0) |
Other | 3 (3.6) | 6 (5.6) | 3 (5.4) | 1 (2.4) |
Heavy mixed growth / no growth | 33 (39.8) | 35 (32.4) | 24 (42.9) | 19 (45.2) |
Culture not performed | 28 (33.7) | 30 (27.8) | 12 (21.4) | 13 (31.0) |
Resistant urine pathogensc | 8 (36.4) | 11 (25.6) | 3 (15.0) | 5 (50.0) |
Urinary white cell count | ||||
< thresholdb | 24 (32.9) | 27 (27.3) | 12 (23.1) | 14 (35.9) |
> thresholdb | 49 (67.1) | 72 (72.7) | 40 (76.9) | 25 (64.1) |
Not performed | 10 | 9 | 4 | 3 |
Blood culture resultsa | ||||
Positive | 4 (4.8) | 1 (0.9) | 2 (3.6) | 7 (16.7) |
E. coli | 0 (0.0) | 0 (0.0) | 1 (1.8) | 3 (7.1) |
Other | 4 (4.8) | 1 (0.9) | 1 (1.8) | 4 (9.5) |
No growth | 19 (22.9) | 4 (3.7) | 28 (50.0) | 28 (66.7) |
Culture not taken | 60 (72.3) | 103 (95.4) | 26 (46.4) | 7 (16.7) |
Resistant blood pathogens | 0 (0.0) | 0 (0.0) | 0 (0.0) | 2 (28.6) |
Antibiotics stopped | ||||
At admission | 17 (24.3) | – | 4 (8.2) | 4 (9.5) |
< 72 h | 24 (34.3) | – | 5 (10.2) | 8 (19.0) |